Objective: To introduce the paper by Kuhn et al. “Informatics and Medicine: From Molecules to Populations” and the papers that follow on this special topic in this issue of Methods of Information in Medicine, which opens a debate on the Kuhn et al. paper’s assertions by an international panel of invited researchers in biomedical informatics. Method: An introductory summary and comparative revie...

In this paper, we integrate goal programming (GP), Taylor Series, Kuhn-Tucker conditions and Penalty Function approaches to solve linear fractional bi-level programming (LFBLP)problems. As we know, the Taylor Series is having the property of transforming fractional functions to a polynomial. In the present article by Taylor Series we obtain polynomial objective functions which are equivalent...