Cefazolin, a new cephalosporin derivative, was studied in the treatment of 105 hospitalized patients with a variety of infections including endocarditis, pneumonia, and urinary and soft tissue infections, and was found to be effective in 104 patients. Cefazolin was also tested in vitro and shown to be effective against staphylococci, pneumococci, Escherichia coli, Klebsiella sp., and Proteus mi...

I recently read the interesting report by Tejera et al. about Ralstonia pickettii, a gram-negative germ formerly of the Burkholderia group that infected two patients on hemodialyisis. The first was a 65-year-old man with a chronic kidney disease and native arteriovenous fistula who, and was managed in the intensive care unit (ICU) because of development of a septic shock. The transesophageal ec...

In chronic myeloid leukemia (CML), the occurrence of blastic transformation is rare. Treatment outcome is generally poor. Allogeneic stem cell transplantation (allo-SCT) is the only potentially curative treatment option for advanced-phase CML. Infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates are associated with high morbidity and mortality rates, particularly in p...

pneumonia (CAP), including aspiration pneumonia, and a greater incidence of pulmonary tuberculosis compared with the general population. This relates to smoking, alcohol abuse, poor nutrition and homelessness. Organisms commonly causing CAP in this group include Streptococcus pneumoniae, S aureus, Haemophilus influenzae and Klebsiella pneumoniae.11,12 Septic pulmonary emboli can seed from injec...

The medical records of all patients discharged with the diagnosis of "infective endocarditis", "subacute bacterial endocarditis (SBE)," "acute bacterial endocarditis (ABE)," and "bacterial endocarditis" from March 1977, to February 1987, were reviewed. 84 cases fulfilled the criteria of endocarditis. Sixty-one percent were male and the mean age was 25.7 years. 57% were culture-negative and ...

conclusions endocarditis is an important disease with a high mortality rate if not treated appropriately. therefore, these patients need more attention. in echocardiography, vegetation and complications of ie such as abscess and paravalvular leakage can be detected. results we studied 35 patients, 45% male and 55% female with a mean age of 56.36 ± 12.44 years. fever (80%) and chills (65.7%) wer...

bacterial endocarditis is a serious disease that could occur after invasive dental procedures. despite a large number of papers written about the knowledge of prevention of bacterial endocarditis among health care workers in western countries, little is known about awareness of this subject among practitioners and students in other countries. the purpose of the present study was to assess the k...

infective endocarditis can complicate with ischemic stroke. neurological complications develop in 20-40% of all patients with infective endocarditis. these are mainly due to vegetation embolism.this report represents a case of 30 years old female patient who presented with features of heart failure new york heart association (nyha) class iv with infective endocarditis and left hemiparesis. on e...

we report the case of a male patient with community‑acquired quadruple‑valve endocarditis on presumed normal native valves.this patient had originally presented elsewhere with generalized edema and malaise and had been diagnosed with suspicious endocarditis and renal dysfunction, for which he unfortunately received incomplete treatment. transthoracic and transesophageal echocardiographic ex...