Introduction. Opiates are traditionally used for treatment of some acute heart disorders. There are only few reports on the effects of long-term treatment of cardiovascular diseases with morphine. This study aimed to investigate the effects of chronic low-dose morphine use on the cardiovascular system in two-kidney one-clip (2K1C) hypertensive rats. Materials and Methods. Male Wistar rats were ...

Isolated pleural involvement is rare in Kaposi sarcoma (KS). We report an unusual case of bloody pleural effusion and ascites associated with KS in a kidney transplant recipient. A 50-year-old man who had received kidney transplantation from a living unrelated donor presented with a massive left-side pleural effusion, ascites, and a skin lesion. The pleural effusion and ascites were bloody. The...

Introduction. Recent studies have shown that serum microRNAs have specific expression patterns in some diseases, indicating the potential of using microRNAs to aid diagnosis. This study estimated the levels of microRNAs in patients with nephrotic syndrome compared with healthy controls. Materials and Methods. In this study, real-time quantitative polymerase chain reaction was used to explore wh...

background: cyclosporine a (csa) is an immunosuppressant with therapeutic indications in various immunological diseases; however, its use is associated with chronic nephropathy. oxidative stress has a crucial role in csa-induced nephrotoxicity. the present study evaluates the protective effect of edaravone on csa-induced chronic nephropathy and investigates its antioxidant and nitric oxide modu...

The Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) investigators conducted a multinational, multicentre, prospective, epidemiological survey of acute renal failure (ARF) in intensive care unit (ICU) patients [1], with the intention of determining the association between outcome and different epidemiological parameters: period prevalence of ARF, aetiology, illness severity ...