BACKGROUND Although nasal polyps are one of the most frequent diseases, their etiopathogenesis remains unclear.Since eosinophils are the main inflammatory cells in the substantial proportion of nasal polyp tissues, they are considered potentially responsible for the etiopathogenesis and prognosis of the disease. Aim of this study was to investigate the relation between mucosal and peripheral eo...

Kennedy disease, a degenerative disorder characterized by androgen-dependent neuromuscular weakness, is caused by a CAG/glutamine tract expansion in the androgen receptor (Ar) gene. We developed a mouse model of Kennedy disease, using gene targeting to convert mouse androgen receptor (AR) to human sequence while introducing 113 glutamines. AR113Q mice developed hormone and glutamine length-depe...

We use the April 1993 Current Population Survey to examine the health insurance coverage decisions of the unemployed and to simulate the potential effects of the new Kassebaum-Kennedy legislation. After controlling for demographic characteristics, COBRA eligibility raises the probability of health insurance coverage by 0.095, while eligibility for spouse employer insurance increases the likelih...

At the age of 43 years, John F. Kennedy was the youngest man ever elected president. Throughout both his campaign and his presidency, he was portrayed as the epitome of youth and vigor. In fact, he had the most complex medical history of anyone to occupy the White House. The recent opening of his White House medical records has provided researchers greater insight into the multiple medical cond...

THE SURGEONS I first met Mr (as he was then) George Johnston and Mr Terence Kennedy in the old Wards 5 and 6 in the Royal Victoria Hospital (now demolished) 2 when I was a student. They had strikingly different personalities-Mr Kennedy was more than a little daunting but both were constantly stimulating and renowned teachers. The teaching ward rounds revealed surgical cases in the true sense of...

The issues raised by Ian Kennedy in the course of his 1980 Reith Lectures on medical ethics are also of concern to Great Britain's Patients Association. Ackroyd, as Chairman of the Association, does not however share Kennedy's view that the consumerism model for regulating abuses is appropriate to medical care. She would prefer to have the Health Service Commissioner authorized to investigate...