Este artigo trata, sob uma perspectiva discursivo-funcional, do tradicionalmente chamado, em gramáticas de língua portuguesa, aposto oração, com o objetivo analisar suas funções textual-discursivas. A base teórica é a Gramática Discursivo-Funcional (GDF), Hengeveld e Mackenzie (2008), estudos descritivos sobre aposição, tais como Quirk et al. (1985), Meyer (1992), Hannay Keizer (2005), (2015), ...

The Amsterdam Compiler Kit is an integrated collection of programs designed to simplify the task of producing portable (cross) compilers and interpreters. For each language to be compiled, a program (called a front end) must be written to translate the source program into a common intermediate code. This intermediate code can be optimized and then either directly interpreted or translated to th...

Nguyen M-HT, Dudycha SJ, Jafri MS. Effect of Ca on cardiac mitochondrial energy production is modulated by Na and H dynamics. Am J Physiol Cell Physiol 292: C2004–C2020, 2007. First published March 7, 2007; doi:10.1152/ajpcell.00271.2006.—The energy production of mitochondria in heart increases during exercise. Several works have suggested that calcium acts at multiple control points to activat...

The inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R) channel is crucial for the generation and modulation of intracellular Ca(2+) signals in animal cells. To gain insight into the complicated ligand regulation of this ubiquitous channel, we constructed a simple quantitative continuous-time Markov-chain model from the data. Our model accounts for most experimentally observed gating behavio...

A novel voltage-clamp protocol was developed to test whether slow inactivation of Ca2+ current occurs during bursting in insulin-secreting cells. Single insulin-secreting HIT cells were patch-clamped and their Ca2+ currents were isolated pharmacologically. A computed beta-cell burst was used as a voltage-clamp command and the net Ca2+ current elicited was determined as a cadmium difference curr...