A case of the surdocardiac syndrome of Jervell and Lange-Nielsen, with prolonged QT interval in the electrocardiogram at birth, is described. The affected girl presented 3 1/2 years later with severe iron deficiency anaemia, despite apparently adequate nutrition. At the age of 4 1/2 years she had a sudden attack of unconsciousness. Treatment with the beta-adrenoceptor blocker practolol was star...

Two heritable syndromes possibly genotypically related and manifesting prolonged QT (or QU) interval and TU wave changes, sinus bradycardia, syncopal attacks, ventricular arrhythmias, and frequently sudden death, are recognized respectively with (Jervell and Lange-Nielsen, 1957) and without (Romano, Gemme, and Pongiglione, I963; Ward, I964) profound childhood perceptive deafness. We report here...

It is shown that there is a second properly normalized KNO scaling function, nPn(n/n̄) = φ(z), which has certain advantages in the analysis of KNO scaling. First, the nPn are not influenced by the statistical and systematic uncertainties of n̄ hence φ(z) provides more selective power than the original KNO scaling function n̄Pn(n/n̄) = ψ(z). Second, the new scaling function generates scale parameter...