Nakaura, Hiroyuki, Sachio Morimoto, Fumi Yanaga, Masashi Nakata, Hirofumi Nishi, Tsutomu Imaizumi, and Iwao Ohtsuki. Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy. Am. J. Physiol. 277 (Cell Physiol. 46): C225–C232, 1999.—A splice donor site mutation in intron 15 of the cardiac troponin T (TnT) gene has been shown to cause familial hyper...

Shimojo, Nobutake, Subrina Jesmin, Sohel Zaedi, Seiji Maeda, Masaaki Soma, Kazutaka Aonuma, Iwao Yamaguchi, and Takashi Miyauchi. Eicosapentaenoic acid prevents endothelin-1induced cardiomyocyte hypertrophy in vitro through the suppression of TGF1 and phosphorylated JNK. Am J Physiol Heart Circ Physiol 291: H835–H845, 2006. First published February 24, 2006; doi:10.1152/ajpheart.01365.2005.—The...

One of the first metabolic products of tryptophan to be reported was kynurenic acid, which was isolated by Ellinger in 1904 (1) from the urine of dogs that had been fed the amino acid. He characterized the compound correctly except for the assignment of the carboxyl group to the 3 position in the quinoline ring, but its correct location at the 2 position was determined soon afterward (2). Anoth...

the two-spotted spider mite, tetranychus urticae koch (acari: tetranychidae), is an economically important pest of ornamental plant in iran. the population abundance and spatial distribution were studied on five rosa cultivars including maroussia, wendela, elderado, wenedetta, and hot lady during two growing seasons of 2011 and 2012 in greenhouse. the k parameter, index of dispersion, lloyd’s m...

the sunn pest, eurygaster integriceps put. is an important pest of wheat in firozabad region of ardabil province, iran. in this study the spatial distribution of overwintered adult was investigated in rainfed wheat fields. then, fixed precision sequential sampling plan was developed and validated for estimating overwintered adult density. iwao's patchiness regression gave a better fit to d...

The artificial allosteric molecule, gable porphyrin metal complexes, were prepared by connecting two independent metal porphyrin molecules by covalent bond. The author would like to discuss mostly on allosteric mechanism of the artificial allosteric systems. Our gable porphyrin system behaves similarly to natural Hb, binding small molecules like CO, 02: or base, cooperatively. The original stru...

* Work supported by grants from the Rockefeller Foundation, the Williams Waterman Fund for the Combat of Dietary Diseases and The Nutrition Founldation, Inc. The authors are indebted to Miss Susanne McLean for assistance in carrying out experiments. 1 von Euler, H., Schlenk, F., Melzer, L., and Hogberg, B., Z. physiol. Chem., 258, 212-218 (1939). 2 Dann, W. J., Jour. Biol. Chem., 141, 803-808 (...

noma. Cancer 1996;77:2233–9. (5) Tada M, Omata M, Ohto M. Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma. Gastroenterology 1991;100:233–8. (6) Yanagisawa A, Ohtake K, Ohashi K, Hori M, Kitagawa T, Sugano K, et al. Frequent c-Kiras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation. Cancer Res 1993;53:953–6. (7) M...

1. Pu S, Han F, Ge B. Isolation and characterization of methicillin-resistant Staphylococcus aureus strains from Louisiana retail meats. Appl Environ Microbiol. 2009;75:265–7. doi:10.1128/AEM.0111008 2. Weese JS, Avery BP, Reid-Smith RJ. Detection and quantifi cation of methicillinresistant Staphylococcus aureus (MRSA) clones in retail meat products. Lett Appl Microbiol. 2010;51:338–42. doi:10....