The human epidermis has evolved out of Africa. Increased involucrin (IVL) expression in the skin is associated with a near selective sweep Northern European populations compared to African. significance for this positive selection not clear. Our functional studies using Ivl-/- mice recently determined requirement positively regulate Vitamin D receptor and its activity epidermis. mouse treated M...

BackgroundCoronary calcification impairs stent delivery and optimal expansion, a significant predictor of subsequent thrombosis restenosis. Current calcium ablative technologies may be limited by guidewire bias periprocedural complications. Intravascular lithotripsy (IVL) delivers acoustic pressure waves to modify calcium, enhance vessel compliance, optimize deployment. The Disrupt CAD III stud...

Dear Editor: Intravascular large B-cell lymphoma (B-IVL) is listed as a distinct disease entity in the World Health Organization(WHO) classification for lymphoid neoplasms [1]. The disease is rare, and information for its exact frequency among non-Hodgkin lymphoma (NHL) has been extremely limited. There have been several reports mainly from Asian countries describing the different disease frequ...

The purposes of these experiments were to determine possible relationships among certain indices of lipid metabolism and specific gene expression in chickens (Gallus gallus) fed methimazole (MMI) and the subsequent effects of providing supplemental T3 to relieve the effects of MMI. Male, broiler chickens growing from 14 to 28 days of age were fed diets containing 18% crude protein and either 0 ...

We present a 79-year-old Japanese woman diagnosed with cerebral infarction. In spite of enough antiplatelet and anticoagulant therapy, she presented rapidly recurrent strokes three times for 3 months. Magnetic resonance imaging showed progression of bilateral cerebral infarcts, and chest-abdominal computed tomography showed multiple bilateral nodular lesions in the lung and multiple tumor lesio...

Intravascular lymphoma (IVL) is a rare subtype of extranodal diffuse large B-cell lymphoma with a distinct presentation. Anatomically the disease is characterized by the proliferation of clonal lymphocytes within small vessels with relative sparing of the surrounding tissue. The clinical symptoms of the disease are dependent on the specific organ involvement, which most often includes the centr...

Indian River male broiler chickens growing from 7 to 28 d of age were fed on diets containing either 120 or 210 g crude protein and 0 or 1 mg triiodothyronine (T3)/kg diet to study in vitro lipogenesis (IVL). In addition, a carry-over period (180 g crude protein/kg diet from 28 to 40 d of age) was used to test the persistence of prior treatment effects. The higher protein level increased, but T...

Intravascular lymphoma (IVL) is a rare type of extra-nodal lymphoma with an aggressive clinical course characterized by proliferation of large lymphoma cells within the lumina of small vessels. Diagnosis of IVL is extremely difficult because of its varied clinical symptoms and the absence of lymphadenopathy, which requires histological confirmation. We report a case of a patient with Mono-Neuri...

BACKGROUND Uterine leiomyomas represent the gynecological neoplasm with the highest prevalence worldwide. This apparently benign pathological entity may permeate into the venous system causing the so-called intravenous leiomyomatosis of the uterus (IVL). IVL may seldom extend to large caliber veins and reach the right cardiac chambers or pulmonary arteries and cause signs of right sided congest...

Abstract Funding Acknowledgements Type of funding sources: None. Aims Severe coronary calcification is a serious impediment to optimal stent expansion and can lead failure adverse outcomes. We hereby present Indian experience with intravascular lithotripsy(IVL) for the treatment calcific lesions in acute chronic syndromes at our tertiary care center. Methods results This single-center prospecti...