Introduction: The calcium-aluminum rich inclusions (CAIs) represent the oldest objects formed in the Solar System [1], and therefore knowledge of their chemical and isotope compositions is critical for a better understanding of the origin and evolution of our Solar System and its various components, including the Earth. Previous studies on CAIs showed large mass-dependent isotope effects attrib...

The application of stable isotope analysis (SIA) has become a standard scientific approach in Agricultural and Ecological researches and, more in general, in several disciplines such as biology, botany, zoology, organic chemistry, climatology, and nutrition. The main objectives of this paper are (1) to provide a simple definition of stable isotopes and (2) to illustrate analytical measurement m...

A 15-year-old athletic male was hospitalized with back pain and myalgia after standing out in the cold weather watching a soccer match. Hewas passing dark red urine on admission. He took no prescribed or illicit medications. Family history and physical examination was unremarkable. Laboratory analysis revealed a creatine kinase of 113 542 U/L and normal renal function. A diagnosis of rhabdomyol...

[reaction: see text] A bromine-/chlorine-containing mass-tag encoding strategy for a small-molecule OBOC combinatorial library is reported. The resulting MALDI FTMS isotope pattern of each tag clearly defines the component building blocks of each "hit" bead in an 1890-member demonstration library screened on-bead for binding against streptavidin via both enzyme-linked colorimetric and Quantum D...

introduction one of the first principles in the formation of a reserve is mineralogical, construction and mineral textures studies and investigation of paragenetic relations in the ore minerals. in addition, to petrographic studies, isotopic investigates have wide applications in economic geology. in general, copper isotope variability in primary (high temperature) mineralization forms a tight ...

Ticlopidine, an antiplatelet drug, undergoes extensive oxidative metabolism to form S-oxide, N-oxide, hydroxylated and dealkylated metabolites. However, metabolism of ticlopidine via conjugation has not been thoroughly investigated. In this study, multiple data acquisition and processing tools were applied to the detection and characterization of ticlopidine conjugates in rat bile. Accurate ful...

Recent findings based on the oxygen isotope ratios of tree trunk cellulose indicate that the temperature of biomass production in biomes ranging from boreal to subtropical forests converge to an average leaf temperature of 21.4°C. The above conclusion has been drawn under the assumption that biochemically related isotopic fractionations during cellulose synthesis are not affected by temperature...