Treatment of cervical cancer includes combination of external beam radiation therapy (EBRT) and brachytherapy (BRT). Traditionally, coronal images displaying dose distribution from a ring and tandem (R&T) implant aid in construction of parametrial boost fields. This research aimed to evaluate a method of shaping parametrial fields utilizing contours created from the high-dose-rate (HDR) BRT dos...

BACKGROUND Radiation therapy is the mainstay of treatment for nasopharyngeal carcinoma. Importance of tumor coverage and challenges posed by its unique and critical location are well evident. Therefore we aimed to evaluate our radiation treatment plan through dose volume histograms (DVHs) to find planning target volume (PTV) dose coverage and factors affecting it. MATERIALS AND METHODS This r...

The aim is to study the density, isodose depths, and doses at different points in slab-pinewood-slab (SPS) phantom, solid phantom SP34 (made up of polystyrene), and chest level of actual patient for developing heterogeneous chest phantom mimicking thoracic region of human body. A 6 MV photon beam of field size of 10 cm × 10 cm was directed perpendicular to the surface of computed tomography (CT...

BACKGROUND To analyze patterns of local-regional failure after primary intensity modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC). METHODS A total of 370 non-metastatic NPC patients consecutively treated with IMRT (with or without chemotherapy) were analyzed. Radiotherapy was administered using a simultaneous integrated boost (SIB) technique at the total prescribed dose of 66-...

UNLABELLED The detection of myocardial perfusion abnormalities after radiation therapy (RT) has been investigated previously in patients with lymphoma and breast cancer. However, the prevalence and association of such abnormalities with RT in esophageal cancer patients have not been investigated previously. METHODS The prevalence of myocardial perfusion abnormalities detected using gated myoc...

BACKGROUND AND PURPOSE For the first time, delivered dose to the rectum has been calculated and accumulated throughout the course of prostate radiotherapy using megavoltage computed tomography (MVCT) image guidance scans. Dosimetric parameters were linked with toxicity to test the hypothesis that delivered dose is a stronger predictor of toxicity than planned dose. MATERIAL AND METHODS Dose-s...

Introduction: The determination of accurate dose distribution is an issue of fundamental importance in radiotherapy, especially with regard to the fact that the human body is a heterogeneous medium. Therefore, the present study aimed to analyze the density and isodose depth profiles of 6 MV beam in a SP34 slab-wooden dust (pine)-SP34 slab (SWS) heterogeneous phantom.  Materials and Methods: Th...

Introduction: Wedge filters are used in radiotherapy to modify photon beam and improve dose uniformity in the target volume. Determination of wedge dose distribution is important to improve treatment planning accuracy. The utilization of treatment planning software to obtain dose distribution is not always available. In this work an analytical model has been developed to calcu...

In this work isodose curves are obtained by the use of a new dosimetric algorithm using numerical data from percentage depth dose (PDD) and the maximum absorbed dose profile, calculated by Monte Carlo in a 18 MV LINAC. The software allows reproducing the absorbed dose percentage in the whole irradiated volume quickly and with a good approximation. To validate results an 18 MV LINAC with a whole...