Purpose To report a case of a temporal artery biopsy negative anterior ischemic optic neuropathy associated with a recently completed course of pegylated interferon 2 α with ribavirin for chronic hepatitis C. Observations Despite the early presentation with symptoms and prompt treatment with systemic intravenous steroids the patient experienced deterioration of their optic neuropathy over the...

OBJECTIVE To refine the criteria for the diagnosis of amiodarone-related optic neuropathy by including a broader spectrum of clinical features, thus helping to differentiate this entity from nonarteritic anterior ischemic optic neuropathy coincidentally affecting a patient taking amiodarone. METHODS A retrospective case review of 22 patients who developed optic neuropathy while taking amiodar...

INTRODUCTION Chronic relapsing inflammatory optic neuropathy is a recently described form of recurrent isolated subacute optic neuropathy. The condition is highly responsive to systemic steroid treatment and prone to relapse on steroid withdrawal. A complete work up for demyelination, autoimmune disease and sarcoidosis must be made before considering chronic relapsing inflammatory optic neuropa...

introduction patients with hepatitis c are commonly treated with combination of pegylated interferon alfa-2a and ribavirin. less than 1% of patients receiving this treatment experience very uncommon ophthalmological side effects such as optic neuropathy and vision disorder, which are usually subclinical, mild and reversible, not requiring the withdrawal of the treatment. retinopathy is the most...

BACKGROUND Ischemic optic neuropathy (ION) is an infarction of the anterior or, less frequently, posterior part of the optic nerve, usually due to a disease of small arteries supplying the optic nerve. Carotid stenosis or occlusions are rare causes, and among them, carotid dissections have been so far reported in only 5 cases. METHODS We describe 4 patients with ION (2 anterior and 2 posterio...

BACKGROUND We conducted this study to report the demographics and clinical profile of patients with nonarteritic anterior ischemic optic neuropathy referred to a referral neuro-ophthalmology center in Iran. METHODS During a five-year period, 107 patients with nonarteritic anterior ischemic optic neuropathy were studied. A detailed history of previous or current systemic diseases was obtained ...

Beta interferon − INF 1b: Betaferon® and Extavia® (vial 250 g) INF 1a: Avonex® (vial 30 g); Rebif® (vial 22–44 g). Both also in syringes and preloaded containers. RR MS Pseudo-fever syndrome, depression, psychiatric disorders, moderate myelosuppression, hypotension, high liver enzymes, cough, dyspnea, proteinuria, OHT, hyperuricemia, KI, neuropathy, confusion, edema, hair loss, digestive altera...

The anterior ischemic optic neuropathy is an uncommon complication of alpha-Interferon treatment, characterized by the either temporary or permanent diminishing in visual acuity. We are hereby presenting the clinical case of an anterior ischemic optic neuropathy (non-arteritic form) complicating interferon therapy for Chronic Hepatitis C. In such cases we recommend ophthalmological examinations...

OBJECTIVES To determine whether early recognition and detection of thrombocytosis in patients with giant cell arteritis can help secure an earlier diagnosis, and whether it can help differentiate cases of arteritic optic neuropathy from other forms of optic neuropathy. METHODS Medical and ophthalmologic records from 1993 to 1998 of the authors' patients with biopsy-proven temporal arteritis v...

purpose: to report complications involving the posterior segment after laser assisted in situ keratomileusis (lasik) in 5 myopic patients ranging in age from 26 to 38 years. patients and findings: case one developed bilateral cilioretinal artery obstruction in association with ischemic optic neuropathy. case two presented with nonsimultaneous bilateral delayed-onset optic neuropathy. in case th...