نتایج جستجو برای: isatin

تعداد نتایج: 789  

2014
Garima Mathur Sumitra Nain

Isatin (1H-indole-2,3-dione) and its analog, are versatile substrates which acts as a precursor for large number of pharmacologically active compounds, thus having a significant importance in the synthesis of different heterocyclic compound.Isatin shows varity of biological activities such as antimicrobial, anticancer, antiviral, anticonvulsant, antiinflammatory and analgesic.This review focuse...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ایلام - دانشکده علوم پایه 1393

دراین پایان نامه دوکاتالیزگر نانومغناطیسی برای شیمی گزینی اکسایش سولفیدها به سولفوکسیدها تهیه و مورد استفاده قرار گرفتند.سولفوکسیدها حدواسط های مهم سنتزی برای ساختن مولکول هایی هستند که اهمیت بیولوژیکی و شیمیایی دارند. در طی این کار zr(iv)-isatin-fe3o4 و cu(ii)-isatin-fe3o4به عنوان کاتالیزگرهای موثر برای اکسایش سولفیدها به سولفوکسیدها سنتز و مورد استفاده قرار گرفتند.لازم به ذکر است که کاتالیزگر...

Mohammad K Mohammadi

An efficient and mild methodology for rapid and efficient synthesis of isatin Schiff bases was described under microwave irradiation and solvent free condition.aromatic or heterocyclic Primary amines and isatin could be selectively reacted under microwave irradiation into the corresponding isatin Schiff bases in high yields and short reaction time.  

Journal: :iranian journal of pharmaceutical sciences 0
bharat bhusan subudhi department of pharmaceutical sciences, utkal university, vanivihar, bhubaneshwar-751004, orissa, india prasanna k. panda department of pharmaceutical sciences, utkal university, vanivihar, bhubaneshwar-751004, orissa, india dinabandhu bhatta department of pharmaceutical sciences, utkal university, vanivihar, bhubaneshwar-751004, orissa, india aditya jena department of pharmaceutical technology, yadavpur university, kolkata-700032, india

the role of cu, zn and co in human physiology is well documented. isatin and glycine have inhibitory effects on central nervous system. to capitalize on these features metal complexes of isatin-3-glycine were prepared and evaluated for anticonvulsant activity. the cu (ii) complex was found to be most active among the compounds. the compounds were screened against staphylococcus aureus, escheric...

2017
Mohammad Mohsin

Isatin (3a), isatin 3-carbohydrazone (4a), 5-spiro (isatin) 2-(N-acetyl hydrazino) 4-(N-acetyl)-∆2-1,3,4 oxadiazoline (5a), and 5-spiro (isatin) 2-hydrazino∆2-1,3,4 oxadiazoline (6a) had been synthesized from the unsubstituted oximinoacetanilide (2a). 4-Chlorooximinoacetanilide (2b), 5-chloroisatin (3b), 5-chloroisatin 3-carbohydrazone (4b) and 5-spiro (5-chloroisatin) 2-(N-acetyl hydrazino) 4...

Journal: :Molecules 2007
Aliasghar Jarrahpour Dariush Khalili Erik De Clercq Chanaz Salmi Jean Michel Brunel

Twelve new bis-Schiff bases of isatin, benzylisatin and 5-fluoroisatin 3a-3l were prepared by condensation of isatin, benzylisatin and 5-fluoroisatin with primary aromatic amines. The chemical structures of the products were confirmed by 1H- and 13CNMR, IR and mass spectral data. The compounds were screened for antiviral activity against a panel of DNA and RNA viruses. Minimum cytotoxic and min...

2011
Gang Chen Ye Wang Xiaojiang Hao Shuzhen Mu Qianyun Sun

To develop more potent small molecules with enhanced free radical scavenger properties, a series of N-substituted isatin derivatives was synthesized, and the cytoprotective effect on the apoptosis of PC12 cells induced by H2O2 was screened. All these compounds were found to be active, and N-ethyl isatin was found with the most potent activity of 69.7% protective effect on PC12 cells. Structure-...

Journal: :The Spanish journal of psychology 2006
Igor P Ashmarin Raisa A Danilova Olga I Rud'ko Maria V Belopolskaya Maria F Obukhova Elena V Shmalgausen

The inhibitor of monoaminooxydase isatin and the ligand of B-receptors cholecystokinin-4 play a significant role in the suppression and induction of depressive and anxiety states. We induced the formation of auto-antibodies to these compounds against their conjugates with antigen-carrier by immunization of white rats. The result was long-term (more than 2 months) stimulation of depressive and a...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید