Human calprotectin (CP) is a metal-chelating antimicrobial protein of the innate immune response. The current working model states that CP sequesters manganese and zinc from pathogens. We report the discovery that CP chelates iron and deprives bacteria of this essential nutrient. Elemental analysis of CP-treated growth medium establishes that CP reduces the concentrations of manganese, iron and...

Biological and nano fertilizers are alternative supplements to chemical security for the sustainability of agricultural production. This study is present investigate effect biological on quantitative qualitative yield cow pea during two crop years (2018-2019 2019-2020) in research farm South Agricultural Research Education Center Kerman province, Iran. experiment was carried out factorial desig...

Sorting of endocytic ligands and receptors is critical for diverse cellular processes. The physiological significance of endosomal sorting proteins in vertebrates, however, remains largely unknown. Here we report that sorting nexin 3 (Snx3) facilitates the recycling of transferrin receptor (Tfrc) and thus is required for the proper delivery of iron to erythroid progenitors. Snx3 is highly expre...

Across many environments, nitrate (NO_3(-)) is an important form of N available for microorganisms and photosynthetic organisms. Accurate NO_3(-) measurements are important for examining N cycling and retention in terrestrial and aquatic ecosystems, but a common method of NO_3(-)) analysis can underestimate NO_3(-)) concentrations when soluble iron is present (iron > 10 mg L(-1)). The basic met...