iron is essential to erythrocyte oxygen transport and is a catalyst for oxidative metabolism in all cells. iron is absorbed by the duodenum and requires an acidic environment for optimal absorption. iron is found for 70% in erythrocytes, and 30% in storage, and a small amount in myoglobin and cytochromes. iron supplementation reduces anemia in breastfed infants and increases in significant dose...

background: a close relationship has been reported between level of serum iron and ischemic heart diseases which is either brought about through direct effect of serum iron on myocardial cells or as an indirect result of elevated serum lipid profile. a widespread use of iron supplements has been observed due to the high prevalence of iron deficiency anemia. yet an elevated serum lipid is strong...

BACKGROUND In breastfed infants, iron deficiency at <6 mo of life, although uncommon, is observed in industrialized countries. Iron supplementation starting at an early age may prevent iron deficiency. OBJECTIVE The study assessed the effect of early iron supplementation of breastfed infants and tested the hypothesis that iron supplementation enhances iron status. Potential adverse effects (t...

Oxidative stress is believed to be important in physiological aging and age-related diseases. Iron is a potent pro-oxidant implicated in several age-related diseases. While serum ferritin, as an estimate of body stores of iron, has been shown to increase with age, few studies have directly addressed the effect of age on human neural tissue iron levels. We used atomic absorption spectrophotometr...

archaeological excavations on the western part of the central iranian plateau, known as the qazvin plain provides invaluable information about the sedentary communities from early occupation to the later prehistoric era. despite the past archeological data, chronological studies mostly rely on the relative use of the bayesian modeling for stratigraphically-related radiocarbon dates. the current...

AIM To quantify age-dependent iron deposition changes in healthy subjects using Susceptibility Weighted Imaging (SWI). MATERIALS AND METHODS In total, 143 healthy volunteers were enrolled. All underwent conventional MR and SWI sequences. Subjects were divided into eight groups according to age. Using phase images to quantify iron deposition in the head of the caudate nucleus and the lenticula...

Background: Coronary heart disease is a common disease after adolescence. Strong epidemiological evidence is available that iron is an important factor in coronary artery disease. Therefore this study was done to assess the relationship between iron stores and coronary artery disease. Materials and methods: 208 subjects with cardiovascular disease were included in the study. Personal informati...

Treatment of newborn pigs with supplemental iron is a common procedure utilized to prevent neonatal anemia. The aim of this study was to investigate the hepatic distribution and intracellular metabolism of iron-dextran, a widely used colloidal-iron-carbohydrate preparation. Piglets were injected intramuscularly with iron-dextran (50 mg Fe/kg body wt) at 1 d of age. Hepatocytes and sinusoidal ce...

OBJECTIVE To evaluate the prevalence of anemia, iron deficiency and iron deficiency anemia in a cohort of children. METHODS A cohort study nested in a randomized field trial. Children were recruited at birth at the maternity unit of the only public hospital in the city of São Leopoldo, southern Brazil. This study assessed iron status (hemoglobin and serum ferritin) when children were 12-16 mo...