نتایج جستجو برای: ira

تعداد نتایج: 1475  

Journal: :JAMA ophthalmology 2013
Ira H Schachar Sarwar Zahid Grant M Comer Maxwell Stem Asa G Schachar Stephen J Saxe Thomas W Gardner Victor M Elner Thiran Jayasundera

IMPORTANCE Accurate assessment of disease burden and determination of disease progression are challenging in dry age-related macular degeneration (AMD). We assessed the utility of quantified fundus autofluorescence in (FAF) the evaluation and follow-up of dry AMD. OBJECTIVE To develop a method for quantitative FAF image analysis that is capable of stratifying severity of nonexudative AMD. D...

2016
Hironori Shimamoto Shingo Iwano Hiroyasu Umakoshi Koji Kawaguchi Shinji Naganawa

BACKGROUND To investigate the correlation between iodine-related attenuation of dual-energy computed tomography (DE-CT) and the histopathological invasiveness of surgically resected primary non-small cell lung cancers (NSCLCs) ≤ 3 cm in diameter. METHODS We selected 63 consecutive NSCLC lesions from 60 patients (32 males, 28 females; age range, 39-85 years; mean age, 68 years). After injectio...

Journal: :Circulation 2014
Ingo Hilgendorf Igor Theurl Louisa M S Gerhardt Clinton S Robbins Georg F Weber Ayelet Gonen Yoshiko Iwamoto Norbert Degousee Tobias A W Holderried Carla Winter Andreas Zirlik Herbert Y Lin Galina K Sukhova Jagdish Butany Barry B Rubin Joseph L Witztum Peter Libby Matthias Nahrendorf Ralph Weissleder Filip K Swirski

BACKGROUND Atherosclerotic lesions grow via the accumulation of leukocytes and oxidized lipoproteins in the vessel wall. Leukocytes can attenuate or augment atherosclerosis through the release of cytokines, chemokines, and other mediators. Deciphering how leukocytes develop, oppose, and complement each other's function and shape the course of disease can illuminate our understanding of atherosc...

Journal: :Molecular biology of the cell 2008
Carmen Nevado Manuel Benito Angela M Valverde

We have investigated the unique role of the insulin receptor (IR) and the balance of its isoforms A and B in the regulation of apoptosis in simian virus 40 (SV40)-immortalized neonatal hepatocytes. Immortalized hepatocytes lacking (HIR KO) or expressing the entire IR (HIR LoxP), and cells expressing either IRA (HIR RecA) or IRB (HIR RecB) have been generated. IR deficiency in hepatocytes increa...

Journal: :Scandinavian journal of gastroenterology 2017
Kalle Landerholm Maie Abdalla Pär Myrelid Roland E Andersson

OBJECTIVES Ileorectal anastomosis (IRA) affects bowel function, sexual function and reproduction less negatively than ileal pouch anal anastomosis (IPAA), the standard reconstruction after colectomy for ulcerative colitis (UC). In younger UC patients, IRA may have a role postponing pelvic surgery and IPAA. The aim of the present study was to investigate the survival of IPAA secondary to IRA com...

Journal: :EBRI issue brief 2012
Craig Copeland

In 2010, IRA owners were more likely to be male, especially those whose accounts originated from a rollover or were a SEP/SIMPLE. Among all IRA owners in the database, nearly one-half (45.8 percent) were ages 45-64. The average and median IRA account balance in 2010 was $67,438 and $17,863, respectively, while the average and median IRA individual balance (all accounts from the same person comb...

Journal: :CoRR 2007
Sumit Kumar Jha

This paper presents the design of a novel distributed algorithm d-IRA for the reachability analysis of linear hybrid automata. Recent work on iterative relaxation abstraction (IRA) is leveraged to distribute the computational problem among multiple computational nodes in a non-redundant manner by performing careful infeasibility analysis of linear programs corresponding to spurious counterexamp...

2007
Carmen Nevado Manuel Benito Angela M. Valverde

We have investigated the unique role of the insulin receptor (IR) and the balance of its isoforms A and B in the regulation of apoptosis in SV40-immortalized neonatal hepatocytes. Immortalized hepatocytes lacking (HIR KO) or expressing the entire IR (HIR LoxP), and cells expressing either IRA (HIR RecA) or IRB (HIR RecB) have been generated. IR deficiency in hepatocytes increases sensitivity to...

2015
S. Rasoul V. van Ommen J. Vainer M. Ilhan L. Veenstra R. Erdem L.A.W. Ruiters R. Theunissen J.C.A. Hoorntje

BACKGROUND There are controversial data regarding infarct-related artery only (IRA-PCI) revascularisation versus multivessel revascularisation (MV-PCI) in ST-elevation myocardial infarction (STEMI) patients with multivessel disease undergoing primary percutaneous coronary intervention (PCI). We performed a meta-analysis comparing outcome in same stage MV-PCI versus IRA-PCI in STEMI patients wit...

2015
Hyukjin Park Young Joon Hong Si Hyun Rhew Sung Soo Kim Young Wook Jeong Hae Chang Jeong Jae Yeong Cho Soo Young Jang Ki Hong Lee Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Myung Ho Jeong Jeong Gwan Cho Jong Chun Park

BACKGROUND/AIMS The aim of this study was to compare the risk of complications and outcome between infarct-related artery (IRA)-only revascularization and multivessel (MV) revascularization in patients with acute myocardial infarction (MI) with renal insufficiency and MV disease. METHODS A total of 1,031 acute MI patients with renal insufficiency and MV disease who were registered in the Kore...

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