conclusions: this study showed acceptable sensitivity and specificity of qtcd and qtd in comparison to lvmi; it seems that standard ecg can be used for early diagnosis of cardiac involvement in asymptomatic patients with thalassemia major. patients and methods: in a case-control study, 60 patients older than ten years of age with thalassemia major who received regular blood transfusion and iron...

breast cancer is a major cause of mortality in women due to malignant diseases and is the most prevalent type of cancer in western countries. according to investigations which has been done in iran so far, the prevalence of disease in our country is also very high, therefore complete attention to clinical and pathological findings of this disease would be extremely essential. in this study, the...

this commentary considers the potential role of patient and public involvement in implementation. developing an analytical thread from the resource-based view of the firm, we argue that this involvement may create unique resources that have the capacity to enhance the impact of implementation activity for healthcare organisations.

introduction: the use of ossicular graft material in ossicular chain reconstruction has significantly improved hearing results hearing after tympanoplasty and tympanomastoid surgery for chronic otitis media. today, otologists have a wide array of tools from which to choose, but may find it difficult to know which middle ear implant works best.   materials and methods: a prospective study of 80 ...

BACKGROUND & OBJECTIVES The proportion of malaria cases that are complicated and fatal are not well described in India. Alipurduar sub-division of Jalpaiguri district in West Bengal is highly endemic for malaria. We constructed a retrospective cohort of severe malaria patients admitted in the secondary and tertiary care facilities in Alipurduar to determine the incidence, assess the management,...

Serology is important for the diagnosis and follow-up of human alveolar echinococcosis (AE). However, patient conditions are highly variable among those with AE, and antibody responses in serological follow-up have not been well-defined. We recently described a new AE rat model established by implantation of small AE tissue into a single arbitrary location in the liver; no metastasis and dissem...

Correct use of an adrenalin auto-injector (AAI) is vital in an emergency situation where a person has gone into anaphylactic shock. Studies have shown that nearly half of untrained participants are unable to correctly use an AAI training device after instruction. Emerade is an AAI with a different design for use, with pictures providing instructions. This study aimed to assess intuitiveness and...

Henoch-Schoenlein purpura (HSP) is a vasculitis of the small blood vessels with clinical presentation of a multi-organ involvement syndrome at variable expression in derma, intestine, articulations and kidney. Firstly identified by Heberden, Schoenlein described the purpuric and articular manifestations and Henoch the gastrointestinal and renal features. The combination of various systemic and ...

Over the last two decades, important advances have been made in explaining some pathophysiological aspects of heart failure with preserved ejection fraction (HFpEF) with repercussions for the successful clinical management of the syndrome. Despite these gains, our knowledge for the natural history of clinical progression from the pre-clinical diastolic dysfunction (PDD) until the final clinical...