A prospective series of 20 patients with moderate to severe intraventricular haemorrhage (IVH) was studied for the effect of intraventricular administration of recombinant tissue plasminogen activator (rt-PA) on reduction of haematoma volume and prognosis. On the day of haemorrhage ventriculostomy was performed and 2 to 5 mg of rt-PA were injected via the external ventricular drainage, followed...

BACKGROUND There is a paucity of clinical studies focused specifically on intracerebral haemorrhages of subcortical topography, a subject matter of interest to clinicians involved in stroke management. This single centre, retrospective study was conducted with the following objectives: a) to describe the aetiological, clinical and prognostic characteristics of patients with thalamic haemorrhage...

A method for systematic scanning of the neonatal brain with real-time ultrasound is described, and the linear array is compared with mechanical sector scanners. Anatomical landmarks recognised on axial, coronal, and parasagittal scans are verified by comparison with brain slices at necropsy. A prospective study of 50 infants admitted consecutively to the neonatal unit at this hospital showed in...

The association between measurements of lateral ventricle area (determined by serial ultrasound scans) and outcome was studied in 70 preterm neonates of 33 weeks' gestation or less. The study group was subdivided into four groups according to cranial ultrasonographic findings at 2 weeks postnatal age: group A (n = 15) had isolated periventricular/intraventricular haemorrhage; group B (n = 20) h...

Intraventricular haemorrhage may occur de novo in previously well, term newborn infants. In a group of six neonates a high incidence of posthaemorrhagic hydrocephalus was found. Posthaemorrhagic hydrocephalus may be more common in full term newborn infants than previously recognised.