Intravenous immunoglobulin (IVIg) is a polyclonal immunoglobulin G preparation with potent immunomodulatory properties. The mode of action of IVIg has been investigated in multiple disease states, with various mechanisms described to account for its benefits. Recent data indicate that IVIg increases both the number and the suppressive capacity of regulatory T cells, a subpopulation of T cells t...

The coexistence of a high IgE level and transient hypogammaglobulinemia infancy ( THI ) with atopic dermatitis (AD) is well known, but the marked serum ≥ 1000 IU/mL rare finding. Literature scarce regarding levels in patients AD after treatment immunoglobulin (Ig). We reported female infant 8 months old, severe AD. She was treated intravenous (IVIG) infusion failure conventional therapy. Initia...

Background This study aimed to evaluate the effectiveness of Intravenous immunoglobulin (IVIg) and combination of IVIg and Methylprednisolone for childhood Idiopathic (autoimmune) Thrombocytopenia (ITP) treatment; in addition investigate the related factors to develop chronic form of under 15 years ITP. Materials and Methods This retrospective study conducted on 88 ITP patients that treated wit...

Introduction: Intravenous immunoglobulin (IVIG), which is one of the adjuvant therapy strategies, has been started to be used in critically ill COVID-19 patients due its anti-inflammatory and immunomodulatory effects. 
 Material Method: In our study, it was aimed evaluate effect IVIG intensive care unit on early laboratory findings late lung damage. Twenty-two who met inclusion criteria we...

Intravenous immunoglobulin (IVIG) has been used primarily for immune deficiency patients, and its greatest expansion is seen more and more in the treatment of autoimmune disorders, especially in neurology. The benefits of IVIG treatment include its availability in all treatment centers and its ease of administration in an outpatient setting. This article gives an overview of some autoimmune neu...

BACKGROUND Scleromyxoedema is a variant of papular mucinosis affecting the skin and internal organs. The different therapeutic approaches proposed for scleromyxoedema are still unsatisfactory. Intravenous immunoglobulin (IVIg) has been successfully employed in the treatment of connective tissue diseases and vasculitides. PATIENTS The successful treatment of three cases of scleromyxoedema with...

Intravenous immunoglobulin (IVIG) is used for the treatment of numerous immunodeficiency, immune-mediated, and inflammatory disorders in humans. More recently, it has been described for the therapy of immune-mediated hematologic disease in dogs. While the potential benefits of IVIG are tantalizing, and initial reports in dogs are encouraging, there is a marked paucity of controlled studies in t...

Intravenous immunoglobulin (IVIg) therapy is being increasingly used in a wide range of neurological conditions. However, treatment is expensive and side effects may be severe. A patient with Miller Fisher syndrome who developed cortical blindness as a consequence of occipital infarction precipitated by IVIg is reported on.

Intravenous immunoglobulin (IVIG) has been utilized in patients with recurrent and refractory Clostridium difficile colitis. It is increasingly being used in patients with initial clinical presentation of severe colitis. Herein, we report a case of severe C. Difficile colitis successfully treated with IVIG with a review of the medical literature to identify the optimal timing and clinical chara...

A pediatric case with Bickerstaff’s brainstem encephalitis (BBE), which is a very rare monophasic post-infectious condition characterized by central nervous system involvement, unconsciousness, ophthalmoplegia and ataxia, presented. Twelve years old patient was brought difficulty in eye movements ataxia. On the second day, she became agitated lethargic, then bulbar palsy whole body paralysis de...