BACKGROUND Corticosteroids have anti-inflammatory, analgesic and antiemetic effects but causes severe perineal symptoms when given intravenously. Simultaneous administration of dexamethasone and fentanyl have been known to decrease the duration of perineal pain but its role in alleviating perineal pain has not been studied. Therefore, we hypothesized that fentanyl pretreatment could prevent the...

OBJECTIVES The incidence of fentanyl-induced cough (FIC) during induction of general anesthesia varies around 40% and is undesirable. It increases intracranial, intraocular, and intra-abdominal pressures. This prospective, randomized, double-blind, placebo-controlled study evaluated the effect of dexmedetomidine (DEX) pretreatment on the incidence and severity of FIC. METHODS Altogether 300 p...

Patients were randomly allocated to one of two groups; intravenous or epidural analgesia, with twenty patients in each group. General anesthesia was induced with thiopentone 5-6 mgkg-1 and maintained with 0.8-1.0% isoflurane and 66% nitrous oxide in 33% O2. The trachea was intubated after administration of vecuronium 0.1 mgkg-1. Patients in the epidural analgesia groups then received, by random...

BACKGROUND To evaluate intranasal administration of butorphanol on postoperative pain and early postoperative cognitive dysfunction in old patients undergoing H-uvulopalatopharyngoplasty (H-UPPP). METHODS A total of 260 male patients (65 to 77 years old) with obstructive sleep apnea hypopnea syndrome and scheduled for H-UPPP were divided randomly to receive intranasal butorphanol, intravenous...

BACKGROUND AND METHODS To evaluate the efficacy of postthoracotomy analgesia with intermittent epidural fentanyl. 50 patients were allocated randomly into 2 groups. The first group received intermittent epidural fentanyl and the second group received intermittent intravenous analgesia using pethidine. The variables studied were: pain score; total amount of additional intravenous opioid analgesi...

Purpose. Fentanyl is available as a transdermal system for the treatment of chronic pain in opioid-tolerant patients; however, it carries a black box warning due to both the potency of the product and the potential for abuse. In this report, we describe a case of transbuccal and gastrointestinal ingestion of fentanyl patches and the management of such ingestion. Summary. A 32-year-old man was b...

Introduction: Breakthrough Pain (BTP) is experienced as mild to moderate-severe pain, from only a few seconds hours. It causes decrease in the quality of life and functional capacities. Furthermore, BPT must be recognizable, assessed, controlled prevent its relapse severity. Case report: A woman, 45 years old, having breast cancer along with pulmonary, femur, cervical metastases, came main comp...

Fentanyl is a potent opioid used commonly in acute care because of its rapid onset and short duration of action. It has fewer side effects when compared with commonly available opioids, such as morphine and hydromorphine. We report an unusual side effect of transient aphasia following fentanyl administration. A 61-year-old female presented for an elective embolization of a periophthalmic artery...

A 64-year-old man with left-sided tinnitus since September 2003 underwent left atrial catheter ablation for atrial flutter that he had been experiencing since 1999. For the procedure, he was anesthetized with a cumulative intravenous dosage of 700 mg propofol and 0.5 mg fentanyl over 2.5 hours. The patient's tinnitus had completely disappeared after he awoke from the anesthesia. Ten days after ...