نتایج جستجو برای: intrathecal
تعداد نتایج: 6978 فیلتر نتایج به سال:
OBJECTIVES Intrathecal drug administration using an implanted pump system is well established in intractable spasticity and pain. However, despite continuous advancements in manufacturing technology, adverse events related to the pump and catheter still occur. Most of them, such as migration, damage, disconnection and occlusion, are related to the spinal catheter. The aim of this overview is to...
Intrathecal IgG synthesis is a key biological feature of multiple sclerosis (MS). When acquired early, it persists over time. A growing body of evidence suggests that intrathecal Ig-secreting cells may be pathogenic either by a direct action of toxic IgG or by locally secreting bystander toxic products. Intrathecal IgG synthesis depends on the presence of CNS lymphoid organs, which are strongly...
BACKGROUND Recent efforts to improve the combined spinal epidural (CSE) technique have focused on adding opioids to other classes of analgesics. In this study, the authors used intrathecal neostigmine in combination with intrathecal sufentanil to investigate the usefulness of neostigmine for reducing side effects and prolonging the duration of sufentanil. METHODS One hundred six healthy pregn...
INTRODUCTION Continuous intrathecal infusion of drugs to treat chronic pain and spasticity has become a standard part of the algorithm of care. The use of opioids has been associated with noninfectious inflammatory masses at the tip of the intrathecal catheter, which can result in neurologic complications. METHODS The Polyanalgesic Consensus Conference is a meeting of a group of well-publishe...
Chronic pain may recur after initial response to strong opioids in both patients with cancer and patients without cancer or therapy may be complicated by intolerable side effects. When minimally invasive interventional pain management techniques also fail to provide satisfactory pain relief, continuous intrathecal analgesic administration may be considered. Only 3 products have been officially ...
Intrathecal granuloma formation has commonly been described with morphine therapy. It has been suggested that a high concentration of intrathecal morphine may be responsible for this complication. Much less commonly, intrathecal hydromorphone has been associated with intrathecal granuloma formation. In the current case we report the evaluation and management of an intrathecal granuloma in a pat...
OBJECTIVE To study the use of intrathecal morphine plus PCA for reducing morphine consumption, pain scores, and improving patient-satisfaction. MATERIAL AND METHOD The authors included patients who had received a flank incision for elective kidney surgery. The patients were random into the intrathecal and control groups by block randomization using the sealed envelop technique. The intratheca...
BACKGROUND The use of intrathecal opioids for labor analgesia continues to gain popularity, but there are limited data to guide this use. Previously, the authors established the ED50 for 60 min of labor analgesia from intrathecal sufentanil using an up-down sequential allocation study design. The current study first establishes an ED50 for intrathecal fentanyl using this same study design to es...
BACKGROUND Postoperative pain is a common, distressing symptom following arthroscopic knee surgery. The aim of this study was to compare the potential analgesic effect of dexmedetomidine after intrathecal versus intra-articular administration following arthroscopic knee surgery. METHODS Ninety patients undergoing unilateral elective arthroscopic knee surgery were randomly assigned into three ...
Background and aimsThe efficacy of adding midazolam to intrathecal bupivacaine has been widely documented. The aim of this study was to assess the effects of combination of intrathecal midazolam and lidocaine on postoperative pain.MethodsIn a randomized controlled trial that was performed in 2007 in a teaching hospital of Arak University of Medical Sciences, forty five male patients who were ca...
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