the pharmacokinetic parameters of ceftazidime, a third generation cephalosporin, were investigated in six buffalo calves after single intravenous (iv) and intramuscular (im) administration at a dose rate of 10 mg/kg body weight. ceftazidime concentrations in plasma and urine were determined by microbiological assay. ceftazidime disposition was best fitted by a two-compartmental and a one-compar...

BACKGROUND To compare the efficacy of two routes of prostaglandin E2 administration (Intravenous and Intramuscular) for treatment of missed abortion this study was conducted. Regarding the pilot cases of missed abortion admitted for termination of pregnancy intravenous administration of PGE2 that had higher efficacy compare to intramuscular route, investigators designed this study. METHODS In...

Plasma and aqueous levels of cyclosporin A (CsA) were determined following topical administration of CsA 1% to healthy rabbit eyes and compared with levels obtained when administered to rabbit eyes which had received corneal grafts 7-10 days previously. In addition plasma levels were determined following intramuscular administration of 50 mg CsA and the results compared with those obtained foll...

BACKGROUND Influenza vaccines are recommended for administration by the intramuscular route. However, many physicians use the subcutaneous route for patients receiving an oral anticoagulant because this route is thought to induce fewer hemorrhagic side effects. Our aim is to assess the safety of intramuscular administration of influenza vaccine in patients on oral anticoagulation therapy. MET...

in circumstances such as in vitro fertilization (ivf) or in patients with luteal phase defect, one needs to ensure the establishment of pregnancy as soon as possible. at the same time, a question arises: how can a physician make sure that the β-hcg is of an endogenous source and not the residue of the prescribed drugs (hcg)? in this article we have studied the elimination time of 1m injection o...