The intracellular topology of serotonin transporter (SERT) was examined using mutants containing single cysteine residues in the predicted cytoplasmic domain of the protein. Cysteine residues in each predicted cytoplasmic domain, including the NH2 and COOH termini and the five predicted internal loops, reacted with methanethiosulfonate (MTS) reagents only when the plasma membrane was permeabili...

Abstract. A simplicial complex is said to satisfy complementarity if exactly one of each complementary pair of nonempty vertex-sets constitutes a face of the complex. We show that if a d-dimensional combinatorial manifold M with n vertices satisfies complementarity then d = 0, 2, 4, 8 or 16 with n = 3d/2 + 3 and IMI is a "manifold like a projective plane". Arnoux and Marin had earlier proved th...

in this paper we investigate generalized topologies generated by a subbase ofpreorder relators and consider its application in the concept of the complement. we introducethe notion of principal generalized topologies obtained from the new type of open sets andstudy some of their important properties.

Vehicular Ad-Hoc Networks can enhance road safety and enable drivers to avoid different threats. Safety applications, mobile commerce, and other information services are among different available services that are affected by dynamic topology, vehicle’s speed and node misbehaving. Dynamic topology makes the route unstable and unreliable. So, improving the throughput and performance of VANET thr...

Transmembrane proteins affect vital cellular functions and pathogenesis, and are a focus of drug design. It is difficult to obtain diffraction quality crystals to study transmembrane protein structure. Computational tools for transmembrane protein topology prediction fill in the gap between the abundance of transmembrane proteins and the scarcity of known membrane protein structures. Their pred...

The study of electronic topology in very subtle phase transitions allows us to understand the physical chemical interactions involved. Here, we correlate changes internal compressibility with lone electron pair interactions.

The increasing demand of numerous applications in consumer electronics has increased the number of computing resources in single chip. In such scenario, application needs many computing resources to build a System-on-Chip (SoC). Therefore, interconnection among Intellectual Property (IP) cores becomes another challenging issue. The execution of the system is measured regarding throughput. The t...

This paper presents a novel topology of single-phase multilevel inverter for low and high power applications. It consists of polarity (Level) generation circuit and H Bridge. The proposed topology can produce higher output voltage levels by connecting dc voltage sources   in series and parallel. The proposed topology utilizes minimum number of power electronic devices which helps in reduction o...