نتایج جستجو برای: interleukin 28b polymorphism

تعداد نتایج: 201199  

2017
Zahra Heidari Bita Moudi Hamidreza Mahmoudzadeh-Sagheb Mehrnoosh Moudi

Title: The association between Interleukin-28B gene polymorphisms as a potential biomarker and the risk of Chronic Periodontitis in an Iranian population Authors: Zahra Heidari ([email protected]) Bita Moudi ([email protected]) Hamidreza Mahmoudzadeh-Sagheb ([email protected]) Mehrnoosh Moudi ([email protected]) Version: 2 Date: 03 May 2017 Author’s response to reviews: HAFM-D...

2017
Yi Li Tiantian Wei Lin Yan Zhiqiang Yang Qian Huang Yunying Shi Lanlan Wang

The present genome-wide association study investigated the relationship of interleukin 28B (IL-28B) genetic variants with HBV susceptibility and prognosis of HBV-infected patients. This study aims to examine the role of IL-28B polymorphisms on transplant etiologies and the liver function recovery in Chinese liver transplant recipients.A total of 231 liver transplant recipients were enrolled in ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2013
Yuji Hodo Masao Honda Akihiro Tanaka Yoshimoto Nomura Kuniaki Arai Taro Yamashita Yoshio Sakai Tatsuya Yamashita Eishiro Mizukoshi Akito Sakai Motoko Sasaki Yasuni Nakanuma Mitsuhiko Moriyama Shuichi Kaneko

PURPOSE Several single-nucleotide polymorphisms (SNP) in the interleukin-28B (IL-28B) locus have recently been shown to be associated with antiviral treatment efficacy for chronic hepatitis C (CHC). However, such an association with hepatocellular carcinoma (HCC) is unkno3 we investigated the association between the IL-28B genotype and the biology and clinical outcome of patients with HCC recei...

2012
Xiaodong Shi Yu Pan Moli Wang Dongsheng Wang Wanyu Li Tao Jiang Peng Zhang Xiumei Chi Yanfang Jiang Yanhang Gao Jin Zhong Bing Sun Damo Xu Jing Jiang Junqi Niu

BACKGROUND The interleukin-28B gene (IL28B) locus has been associated with host resistance to hepatitis C virus (HCV) infection and response to PEG-IFN/RBV treatment in western populations. This study was to determine whether this gene variant is also associated with spontaneous clearance of HCV infection, treatment response and IL-28B protein production in Chinese patients. METHODS We genoty...

2013
Yuji Hodo Masao Honda Akihiro Tanaka Yoshimoto Nomura Kuniaki Arai Taro Yamashita Yoshio Sakai Tatsuya Yamashita Eishiro Mizukoshi Akito Sakai Motoko Sasaki Yasuni Nakanuma Mitsuhiko Moriyama Shuichi Kaneko

Purpose: Several single-nucleotide polymorphisms (SNP) in the interleukin-28B (IL-28B) locus have recently been shown to be associated with antiviral treatment efficacy for chronic hepatitis C (CHC). However, such an association with hepatocellular carcinoma (HCC) is unkno3 we investigated the association between the IL-28B genotype and the biology and clinical outcome of patients with HCC rece...

2014
Francisco Jesús Vera Méndez Amaya Jimeno Almazán Clara Smilg Nicolás Begoña Alcaraz Vidal Onofre Martínez Madrid Mar Alcalde Encinas Josefina García García Lorena Martínez Fernández Pablo Conesa Zamora Elena Ruiz Belmonte Paloma Escribano Viñas Javier Trujillo Santos

INTRODUCTION Single-nucleotide polymorphisms (SNPs) in the region of the Interleukin 28B (IL28B) gene on chromosome 19, coding for the interferon (IFN)-λ3, are involved in hepatitis c virus (HCV), spontaneous clearance. There is little information on the degree of liver fibrosis (LF) in HIV patients, who have had spontaneous clearance of HCV. Our objective in this study is to assess the degree ...

Journal: :Annals of hepatology 2014
Hikmet Akkiz Sedef Kuran Ersin Akgöllü Oguz Usküdar Aynur Bekar Süleyman Bayram

BACKGROUND AND AIM Multiple risk factors lead to hepatocellular carcinoma (HCC) including viral infections, mutation and single nucleotide polymorphisms (SNPs). Interleukin 28B (IL28B) gene rs12979860 polymorphism has been shown to be associated with HCC in the different populations, but its association with HCC has not been investigated in the Turkish population. We investigated whether the rs...

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