نتایج جستجو برای: interleukin 1β
تعداد نتایج: 105629 فیلتر نتایج به سال:
Idiopathic recurrent pericarditis (IRP) and adult-onset Still's disease (AOSD) are polygenic autoinflammatory diseases, in the pathogenesis of which pro-inflammatory cytokines from interleukin-1 superfamily play a central role. Aim . To compare serum concentrations proinflammatory glycosylated ferritin (GF) patients with IRP AOSD during an exacerbation. Material methods The study included 15 AO...
Abbreviations: RA: Rheumatoid Arthritis; CIA: Collagen-Induced Arthritis; IL-1β: Interleukin-1β; IL-6: Interleukin-6; IL-17A: Interleukin17A; IFN-γ: Interferon-γ; TNF-α: Tumor; Necrosis Factor-α; GM-CSF: Granulocyte-Macrophage Colony-Stimulating Factor; IL-8: Interleukin-8; MTX: Methotrexate; CSA: Cyclosporine; AZA: Azathioprine; LEF: Leflunomide; CFA: Complete Freund’s Adjuvant; ELISA: Enzyme ...
This study investigated the effect of ethanol stem bark extract Irvingia gabonensis (ESEIG) on sodium arsenite (SA)-induced pro-inflammatory cytokines and hematological perturbations in Wistar rats. Fifty-five rats weighing 100 g - 179 were distributed into eleven groups (n=5). Group 1 had feed water only. 2 received 4.1 mg/kg body weight (kgbw) SA. Groups 3-11 SA and/or ESEIG. Treatment was do...
Objective: Coronary artery disease (CAD) is a pathological condition resulting from atherosclerosis in the coronary arteries. Besides traditional risk factors, genetic factors such as single nucleotide polymorphs (SNPs) can be involve process. Inflammation plays role changes throughout atherosclerosis, initiation to progress. In this study, we aimed evaluate effects of lectin-like oxidized LDL ...
Nervonic acid (NA) is a kind of ultra-long-chain monounsaturated fatty acid, which can repair nerve cell damage caused by oxidative stress. Alzheimer's disease (AD) nervous system and often accompanied the decline learning memory capacity. In this study, combined dose D-galactose/AlCl3 was used to establish mouse model AD. Meanwhile, mice were treated with different doses NA (10.95 43.93 mg/kg)...
Ulcerative colitis is chronic and recurrent disease of the gastrointestinal tract with uncertain etiology and incomplete treatment options. N-methyl-d-aspartate (NMDA) receptor suppression has shown anti-inflammatory effects in vitro and in vivo. The aim of present study was to evaluate the role of dizocilpine (MK-801), a noncompetitive NMDA receptor antagonist, on TNBS (trinitrobenzene sulfoni...
BACKGROUND Myocardial infarction (MI) is an ischemic wound that recruits millions of leukocytes. MI-associated blood leukocytosis correlates inversely with patient survival, yet the signals driving heightened leukocyte production after MI remain incompletely understood. METHODS AND RESULTS With the use of parabiosis surgery, this study shows that soluble danger signals, among them interleukin...
Objective: Stevioside is a natural non-caloric sweetener which has been reported to have anti-inflammatory activity. The aim of the present study was to examine in vitro and in vivo effects of stevioside on rats plasma levels of tumor necrosis factor- α (TNF-α), interleukin-1β (IL-1β), TNF-α and IL-1β release from lipopolysaccharide(LPS)-stimulated rat peripheral blood mononuclear cells (P...
Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) mediate the development of numerous infl ammatory lung diseases. Since IL-1β is typically activated in situations where TNF-α is produced, it was hypothesized that IL-1β alters TNF-α–induced proinfl ammatory epithelial cell function by altering TNF receptor shedding and surface abundance. In this study, the impact of IL-1β on TNF-α–medi...
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