We have sequenced a methionine tRNA from mosquito mitochondria, and examined its structure using nucleases S1 and T1 under non-denaturing conditions. The sequence is highly homologous to a putative initiator methionine tRNA gene from Drosophila mitochondria. Its anticodon stem contains a run of three G-C base pairs that is characteristic of conventional initiator tRNAs; however, nuclease S1 ana...

A dencentralized consensus protocol refers to a process for all nodes in a distributed system to collect the information/status from every other node and reach a consensus among them. Two classes of decentralized consensus protocols have been studied before: the one without an initiator and the one with an initiator. While the one without an initiator has been well studied in the literature, it...

Caspases execute cell death. The mechanism of effector caspase activation primarily involves reorganization of active site loops following the activation cleavage. The Induced Proximity hypothesis, originally proposed to explain the activation of initiator caspases, has recently been reinterpreted to be proximity-driven dimerization of initiator caspases, and consequently their activation. The ...

In this paper, we study user profile matching with privacy-preservation in mobile social networks (MSNs) and introduce a family of novel profile matching protocols. We first propose an explicit Comparison-based Profile Matching protocol (eCPM) which runs between two parties, an initiator and a responder. The eCPM enables the initiator to obtain the comparison-based matching result about a speci...

The translation initiator-tRNA plays a crucial role in the initiation of protein synthesis in both prokaryotic and eukaryotic cells, by employing specific base pairing between its anticodon triplet CAU and the general initiation codon AUG in the mRNA. Here we show that the initiator-tRNA may also act, in a manner that is independent of its role in protein translation, as a pre-mRNA splicing reg...

Imploding toroidal detonation waves were used to initiate detonations in propane–air and ethylene–air mixtures inside of a tube. The imploding wave was generated by an initiator consisting of an array of channels filled with acetylene–oxygen gas and ignited with a single spark. The initiator was designed as a low-drag initiator tube for use with pulse detonation engines. To detonate hydrocarbon...