linarin is a flavone glycoside in the plants flos chrysanthemi indici, buddleja officinalis, cirsium setosum, mentha arvensis and buddleja davidii, and has been reported to possess analgesic, antipyretic, anti-inflammatory and neuroprotective activities. in this paper, linarin was investigated for its ache inhibitory potential both in vitro and ex vivo. ellman’s colorimetric method was used for...

The paper by Lu et al.’ appearing recently in Blood adds to the already considerable contributions made by this group supporting the hypothesis that acidic isoferritins play an important regulating role for hemopoietic progenitor cells in vitro. While the evidence in favor of this hypothesis has now become substantial, a number of inconsistencies remain and the term “acidic isoferritin” has nev...

recently, the effects of antimicrobial activity of silver nanoparticles was considered by researcher because of bacterial resistance to antimicrobial agents in chemical.the aim of this study was to evaluate the antimicrobial activity of the gold nanoparticles on escherichia coli. gold nanoparticles are chemically synthesized. standard strain of e. coli was cultured in a nutrient broth. minimum ...

background: myeloperoxidase (mpo), which is abundantly expressed in neutrophils, catalyzes the formation of a number of reactive oxidant species. however, evidence has emerged that mpo-derived oxidants contribute to tissue damage and initiation and propagation of inflammatory diseases, particularly, cardiovascular diseases. therefore, studying the regulatory mechanisms of the enzyme activity is...

objective(s): tyrosinase is a key enzyme in pigment synthesis. overproduction of melanin in parts of the skin results in hyperpigmentation diseases. this enzyme is also responsible for the enzymatic browning in fruits and vegetables. thus, its inhibitors are of great importance in the medical, cosmetic and agricultural fields. materials and methods: a series of twelve kojic acid derivatives wer...

Abstract Introduction: The aim of this study was to identify the antibacterial components in the ethanol extraction of Aloe vera against four clinically frequent pathogenic  bacteria. Materials and Methods: In this in-vitro study, Aloe vera extraction was prepared by dissolving 500 grams of the powder in 5L of 95% ethanol. The antibacterial activity of the extraction against Staphylococcus a...

lipoxygenase(lox) catalyzes irreversible transfer of oxygen molecule to arachidonic and linoleic acid to produce 13 hydroproxy octadecadienoic acid. recent studies showed the involvement of lipoxygenase products, leukotrienes, in inflammations and lipoxygenase pathways acts as mediators of early inflammatory events in atherosclerosis. the aim of the present study was purification and characteri...

objective: alpha-glucosidase, as a carbohydratase catalyses the liberation of alpha-glucose from the nonreducing end of some carbohydrates from foods in digestive tract.  consequently, retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes is one of the therapeutic approaches to decrease the postprandial hyperglycemia. recently, a great deal of attention has been pai...