background: respiratory virus infections in children are a leading cause of morbidity and mortality worldwide. methods : a total of 897 clinical specimens were collected from february 2007 to january 2008 and transported to the na­tional influenza center. two hundred and two samples belonged to children under the age of six from 897 specimens, de­scribed above, were selected. then they were tes...

Influenza A viruses possesses two virion surface glycoproteins including haemagglutinin (HA) and neuraminidase (NA). The NA plays an important role in viral replication and promotes virus release from infected cells and facilitates virus spread throughout the body. To find out any genomic changes that might be occurred on NA gene of avian influenza circulating viruses, we have genetically analy...

Influenza viruses continue to be a major health threat in human and bird populations. The improvements in formulation and production level of the current influenza vaccines are not sufficient to afford complete protection. The continuous antigenic drifts and emergence of endemic and zoonotic strains make influenza vaccine planning difficult. Concern about the emergence of new influenza pandemic...

Single-cell clones have been established from the MDCK cell line, characterized for their morphology and evaluated for their suitability for influenza virus research. Three discrete cell morphotypes were identified using light microscopy. Besides morphological features, the cell types can be distinguished by the level of expression of surface glycans recognized by peanut agglutinin (PNA). All c...

Background: Respiratory infections, especially viral infections, are the most prevalent infection affecting Hajj pilgrims. Commonly 3 major human influenza viruses (A/H1N1, A/H3N2, and B) are responsible for these morbidities. The present study was conducted to develop a statistical report on human influenza in Hajj pilgrims.    Methods: Nasal and throat samples were collected from 2...

although migratory waterfowl is well known to be a major reservoir for avian influenza virus (aiv), there are only few recently published reports about the seroprevalence of aiv in this group of birds. to investigate the aiv antibody status in migratory waterfowl of iran, we collected 217 serum samples from 25 different species of waterfowl during 2003 and 2004. these serum samples were tested ...

Although influenza activity in the United States remained low from October through mid-January, the number and percentage of specimens testing positive for influenza viruses have increased in recent weeks. Laboratory-confirmed influenza infections have been reported from 45 states. The predominant influenza viruses isolated this season have been type A (H3N2) viruses that are well matched by th...

Objectives: Influenza is one of the most important emerging and reemerging infectious diseases in the world. The aim of this study is molecular and phylogenetic analyses of the variations in circulating influenza A/H1N1 virus isolates during 2014-2015 in Iran and investigate on the drug resistance conditions in the related Iranian isolates. Material and Methods: Throat samples from Iranian pat...

Influenza viruses A and B are world-wide major causative agents of human acute respiratory infections. Three subtypes of HA (H1 to H3) and two subtypes of NA (N1 and N2) are found among influenza A viruses that have caused epidemics and pandemics among humans. For the rapid isolation and identification of influenza viruses in clinical samples variety of methods are available but the use of nucl...

Bats harbor many viruses, which are periodically transmitted to humans resulting in outbreaks of disease (e.g., Ebola, SARS-CoV). Recently, influenza virus-like sequences were identified in bats; however, the viruses could not be cultured. This discovery aroused great interest in understanding the evolutionary history and pandemic potential of bat-influenza. Using synthetic genomics, we were un...