PURPOSE In autumn 2009, the swine-origin influenza A (H1N1) virus spread throughout South Korea. The aims of this study were to determine the clinical characteristics of children infected by the 2009 H1N1 influenza A virus, and to compare the rapid antigen and real-time polymerase chain reaction (PCR) tests. METHODS We conducted a retrospective review of patients ≥18 years of age who presente...

BACKGROUND Influenza virus is a worldwide health problem with significant economic consequences. To study the gene expression pattern induced by influenza virus infection, it is useful to reveal the pathogenesis of influenza virus infection; but this has not been well examined, especially in vivo study. AIMS To assess the influence of influenza virus infection on gene expression in mice, mRNA...

BACKGROUND Influenza virus and respiratory syncytial virus (RSV) are among the most common viruses causing infections of the lower respiratory tract in young children. Although there are important differences in the immunopathogenesis of these 2 viral pathogens, little is known about how they affect antigen-presenting cells in children with acute infections. METHODS To characterize the immune...

Though the 2009 worldwide influenza A (H1N1) pandemic has been declared to have ended, the influenza virus is expected to continue to circulate from some years as a seasonal influenza. A rapid antigen test (RAT) can aid in rapid diagnosis and allow for early antiviral treatment. We evaluated the clinical usefulness of RAT using SD Bioline Influenza Antigen Test® kit to detect the influenza viru...

in the february 2006 in two wetlands in northern iran, the mortality among wild swans was observed. paralysis was the most prominent feature of the disease. histologically, diffused necrosis of acinar cells in pancreas, degeneration and necrosis of some neurons in central nervous system (cns), sever necrotic and hemorrhagic enteritis, foci of haemorrahge and myocardial cell necrosis in the hear...

background and aims: influenza (flu) is a respiratory infection in mammals and birds. it is caused by an rna virus in the family orthomyxoviridae. the virus is divided into three main types. influenza virus type a is found in a wide variety of bird and mammal species and can undergo major shifts in immunological properties. hemagglutinin (ha) is an important influenza virus surface antigen that...

INTRODUCTION An outbreak of Streptococcus pneumoniae (pneumococcal) infection complicated by concomitant influenza A on an elderly care ward was detected. CASE PRESENTATION Thirteen patients with hospital-acquired respiratory infections were investigated during the course of the outbreak investigation. Six had a positive BinaxNOW S. pneumoniae urinary antigen test and two patients had culture...

Myrica rubra leaf ethanol extract was added to culture medium of Madino-Darby canine kidney (MDCK) cells inoculated with influenza virus, and the inhibition of influenza virus replication was measured. Myrica rubra leaf ethanol extract showed anti-influenza virus activity irrespective of the hemagglutinin antigen type in the influenza virus type A (H1N1), its subtype (H3N2), and type B.