Zaltoprofen is a nonsteroidal anti-inflammatory drug used as an analgesic, antipyretic, and antinflammatory agent. It selective COX-2 inhibitor also inhibits bradykinin-induced pain responses without blocking bradykinin receptors. prescribed for treating inflammatory conditions caused by various disorders such dental pain, musculoskeletal postoperative lumbar frozen shoulder, osteoarthritis cer...

thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. the pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (cams) and promoting the secretion of inflammatory chemokines and cytokines. dysregulated signaling functions of thro...