Angelicae Gigantis Radix (AGR, Angelica gigas) has been used for a long time as a traditional folk medicine in Korea and oriental countries. Decursinol angelate (DCA) is structurally isomeric decursin, one of the major components of AGR. This study was performed to confirm whether DCA augments pentobarbital-induced sleeping behaviors via the activation of GABAA-ergic systems in animals. Oral ad...

During adolescence, there is a tendency to sleep late and sleep less because of altered psychosocial and life-style changes. Recent studies have demonstrated the link between sleeping less and gaining weight in children, adolescents, and adults. We studied the effect of late sleeping and sleeping less on body mass index (BMI) in medical college freshmen. All participants were adolescents (104 m...

Citrus aurantium L. is commonly used as an alternative treatment for insomnia, anxiety and epilepsy. Essential oil from peel (EOP) and hydroethanolic (70% w/v) extract (HE) from leaves were obtained. Hexanic (HF), dichloromethanic (DF) and final aqueous (AF) fractions were obtained from HE by successive partitions. Swiss male mice (35-45 g) were treated orally with 0.5 or 1.0 g/kg of these prep...

Objective(s) Indigofera tinctoria Linn. of Fabaceae family is claimed to be useful to control epileptic seizures in the Indian system of folkore medicine. This study was designed to evaluate I. tinctoria and to verify the claim. Materials and Methods Seizures were induced in male albino rats with pentylenetetrazole (PTZ). The test group animals were administered ethanolic extract of Indigofer...

background research in the area of herbal psychopharmacology has clearly improved in recent decades. self-administration of herbal medicines has been the most popular therapeutic alternative to standard medicine. objectives since the extract of echium amoenum exhibits an anxiolytic effect, the aim of this study is to evaluate the anxiolytic and hypnotic effects in mice of the aqueous and ethano...

Background: Insomnia, which is difficulty in initiating and maintaining sleep, is a very common experience for many people. Considering the increasing interest in medicinal plants in the past decade, many plants such as Coriandrum sativum, Salvia leriifolia, Salvia reuterana and Stachys lavanduli folia have been used in Iranian traditional medicine to abate insomnia. Objective: The present stu...

objective(s) indigofera tinctoria linn. of fabaceae family is claimed to be useful to control epileptic seizures in the indian system of folkore medicine. this study was designed to evaluate i. tinctoria and to verify the claim. materials and methods seizures were induced in male albino rats with pentylenetetrazole (ptz). the test group animals were administered ethanolic extract of indigofera ...