Understanding the neurochemical basis for cognitive function is one of the major goals of neuroscience, with a potential impact on the diagnosis, prevention and treatment of a range of psychiatric and neurological disorders. In this review, the focus will be on a biochemical pathway that remains under-recognized in its implications for brain function, even though it can be responsible for moder...

Social cognition deficits are observed in a variety of psychiatric illnesses. However, data concerning anxiety disorders are sparse and difficult to interpret. This meta-analysis aims at determining if social cognition is affected in social phobia (SP) or posttraumatic stress disorder (PTSD) compared to non-clinical controls and the specificity of such deficits relatively to other anxiety disor...

ment et qualitativement (méta-analyse de Robinson et al.) [17]. Selon les études, les auteurs retrouvent des diffi cultés au niveau de l’apprentissage, de la mémoire verbale, de la mémoire visuelle, de la mémoire de travail, de l’attention soutenue, de la vitesse de traitement de l’information, des fonctions exécutives. En revanche, ne sont habituellement pas retrouvés de défi cits de l’intelli...

Objectives: Internalizing disorders include disorders, such as major depressive disorder, dysthymia, and somatic disorders. In the diagnostic and statistical manual of mental disorders, fifth edition (DSM-5), post-traumatic stress disorder (PTSD) is recognized as a distinct group, but anxiety is a common symptom. This study aimed to investigate the effectiveness of play therapy programs based o...

BACKGROUND Affective disorders are associated with altered cognitive performance. However, the precise interaction between affect and cognition is unclear. The manipulation of serotonin (5-HT), a neurotransmitter implicated in affect, influences performance on "hot" cognitive tasks that require the processing of affective stimuli, but manipulation of affect via mood induction influences perform...

BACKGROUND Two psychological regulation strategies to cope with psychotic symptoms proposed by the cognitive behavioral tradition were examined in this study: cognitive reappraisal and experiential acceptance. Although cognitive behavior therapy for psychosis has increasing empirical support, little is known about the role of these two strategies using methods of known ecological validity. ME...

Knowledge about the effects of physical exercise on brain is accumulating although the mechanisms through which exercise exerts these actions remain largely unknown. A possible involvement of adult hippocampal neurogenesis (AHN) in the effects of exercise is debated while the physiological and pathological significance of AHN is under intense scrutiny. Recently, both neurogenesis-dependent and ...

Although it is generally acknowledged that experiences of frustration, confusion, and anxiety are embodied phenomena, very little is known about how these processes modulate presumably unconscious, but constantly present, subtle bodily movement. We addressed this problem by tracking the low-level dynamics of body movement, using 1/f noise, pink noise, or "fractal scaling", during naturalistic e...

The role of negative cognition and effect in maintaining psychotic symptoms is increasingly recognized but has yet to be substantiated though longitudinal analysis. Based on an a priori theoretical model, we hypothesized that negative cognition and depressed mood play a direct causal role in maintaining paranoia in people with psychosis and that the effect of mood is mediated by negative cognit...