Journal:
:iranian journal of pharmaceutical research
0
sanjay singh department of pharmaceutics, institute of technology, banaras hindu university, varanasi, 221005, india.
rabinarayan parhi department of pharmaceutics, institute of technology, banaras hindu university, varanasi, 221005, india.
anuj garg department of pharmaceutics, institute of technology, banaras hindu university, varanasi, 221005, india.
the objective of this work was to develop bioadhesive topical gel of aceclofenac with the help of response-surface approach. experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of poloxamer 407 (pl-407 = x1) and hydroxypropylmethyl cellulose k100 m (hpmc = x2)] on the bioadhesive character of gel, rheological property o...