76 www.thelancet.com/infection Vol 9 February 2009 Nicole Léger and Jérôme Depaquit emphasise “the importance of preventing an extension of this anthroponotic species in Europe”, a point also stressed by Dujardin et al, since leishmaniasis is not placed under public health surveillance in Europe. We certainly agree with the authors that the indigenous transmission of Leishmania donovani to Cypr...

This article surveys the history of Cyprus’s conflict and partition to derive historical, tactical, and strategic lessons about how the Cyprus problem should be resolved and about the value of partitions more generally. Cyprus is complex. Tensions between North and South are very low, in part because the partition has been a cause of peace. However, both sides remain pervaded by antagonistic an...

Transthyretin familial amyloid polyneuropathy (TTR-FAP) is an autosomal dominant disorder caused by the extracellular deposition of insoluble amyloid fibrils in the endoneurium. TTR-FAP occurs as a result of transthyretin (TTR) gene mutation, and more than 100 TTR mutation types are recognized [1]. It is a highly disabling and life-threatening disease, characterized by progressive sensorimotor ...

This study aims to understand the role of entrepreneurship in helping British immigrant entrepreneurs integrate into socio-economic environment a small island that suffers from political isolation and describe relatively new idea on how helps such immigrants developed nations. Indeed, previous studies have discussed developing countries fabric countries. research revealed motivational factors s...

Ames dwarf (Prop1 (df/df) ) mice are remarkably long-lived and exhibit many characteristics of delayed aging and extended healthspan. Caloric restriction (CR) has similar effects on healthspan and lifespan, and causes an extension of longevity in Ames dwarf mice. Our study objective was to determine whether Ames dwarfism or CR influence neuromusculoskeletal function in middle-aged (82 ± 12 week...

Declining interest in mathematics and the need to raise the educational standards of youth in this discipline set a critical agenda for the revision of pedagogical practices. Tablet PCs and other mobile devices hold a lot of promise as tools for improving education at all levels. The research discussed in this chapter comes from an ongoing, multifaceted program designed to explore the potential...