Enterovirus 71 (EV71)-associated hand-foot-mouth disease has become a major threat to public health in the Asia-Pacific region. Although T cell immunity is closely correlated with clinical outcomes of EV71 infection, little is known about T cell immunity baseline against EV71 and T cell immunogenecity of EV71 Ags in the population, which has restricted our understanding of immunoprotection mech...

BACKGROUND Schistosomiasis continues to be one of the most prevalent parasitic diseases in the world. Despite the existence of a highly effective antischistosome drug, the disease is spreading into new areas, and national control programs do not arrive to complete their tasks particularly in low endemic areas. The availability of a vaccine could represent an additional component to chemotherapy...

We examined the ability of human lysozyme (HLZM) to enhance the immunogenicity of a methylcholanthrene-induced murine fibrosarcoma in C57BL/10 mice. Following s.c. injec tion of 10" live tumor cells, 100% of mice developed palpable tumors within 16 ±3 (S.D.) days. Prechallenge immunization with 106 irradiated tumor cells with or without complete Freund's adjuvant resulted in protection from tu...

We examined the ability of human lysozyme (HLZM) to enhance the immunogenicity of a methylcholanthrene-induced murine fibrosarcoma of C57BL/10 mice. Following s.c. injection of 10(4) live tumor cells, 100% of mice developed palpable tumors within 16 +/- 3 (S.D.) days. Prechallenge immunization with 10(6) irradiated tumor cells with or without complete Freund's adjuvant resulted in protection fr...

A cell line expressing the CD2v protein of ASFV was generated. The efficient expression determined by immunofluorescence and Western blotting. Ni-affinity purified from supernatant cultures. CD2v-expressing cells showed properties hemadsorption, secreted exhibited hemagglutinating activity. antigenicity immunoprotection ability were evaluated immunizing pigs alone, combined with a cell-line-exp...