The world is threatened by the lethal effects of Coronaviruses (CoVs) that associated with major respiratory disorders. CoVs are large, enveloped, positive-stranded RNA and therefore, it considered a complicated virus structure. spike (S) protein exists in CoV’s structure regulates viral access to host using angiotensin-converting enzyme 2 (ACE2) receptor for both severe acute syndrome Coronavi...

PURPOSE The goal of this study was to determine the role of the neonatal Fc (FcRn) receptor in eliminating intravitreally administered full-length immunoglobulin G (IgG) across the blood-retinal barrier. METHODS FcRn receptor expression in normal and laser photocoagulated retinas was compared quantitatively by real-time RT-PCR. The distribution of intravitreally administered full-length IgG w...

BACKGROUND To control avian coccidiosis with drug-independent strategy effectively and safely, multivalent hyperimmune egg yolk immunoglobulin (IgY) was prepared and its ability to protect against Eimeria tenella infection was evaluated. METHODS Hens were orally immunized with live oocysts of 5 species of Eimeria for six times, antibody titers in serum and yolk were monitored by indirect enzy...

We investigated the effects of ecological context (by comparing data from two consecutive years) and experimentally manipulated nestling developmental conditions (large vs. small brood size) on immune function (immunoglobulin Y [IgY]) and oxidative stress in nestling European starlings Sturnus vulgaris. On the basis of annual differences in chicks' morphological traits and body masses close to ...

Immunoglobulin Y (IgY) represents an important class of antibodies, being present in egg yolk, with relevant medical applications and involving non-invasive methods extraction. However, due to the complexity purification levels required for use most demands application multi-step cost-intensive techniques. Therefore, it is upmost importance develop a biocompatible cost-effective downstream proc...

AIM This study was undertaken to compare the immunoglobulin Y (IgY) level and its efficacy in laying hens of four different breeds of poultry (viz., Vanraja, Gramapriya, BlackRock, and KalingaBrown) and its relative transfer in egg yolk and chick. MATERIALS AND METHODS This study was conducted in 48 apparently healthy laying hens vaccinated with Salmonella inactivated polyvalent vaccine, eggs...

background: to control avian coccidiosis with drug-independent strategy effec-tively and safely, multivalent hyperimmune egg yolk immunoglobulin (igy) was prepared and its ability to protect against eimeria tenella infection was evaluated. methods: hens were orally immunized with live oocysts of 5 species of eimeria for six times, antibody titers in serum and yolk were monitored by indirect enz...

BACKGROUND In any calf rearing system it is desirable to obtain healthy animals, and reduce morbidity, mortality, and economic losses. Bovine syndesmochorial placentation prevents the direct transfer of bovine immunoglobulins to the fetus, and calves are born hypogammaglobulinemic. These calves therefore require colostrum immediately after birth. Colostrum is rich in immunoglobulins (Ig) and it...

recently it has been reported, that immunoglobulin y (igy) can be used instead of polyclonal antibodies extracted from mammals (igg) for the purpose of diagnosis and therapy. these antibodies are found to have better properties in terms of specificity and ease of large-scale production. in addition, igy binds neither to mammalian complement or fc-receptors nor does it interfere with rheumatoid ...

In an attempt to prepare egg yolk immunoglobulin (IgY) to treat and prevent cholera, hens were immunized by a mixture of heat- or formalin-killed Vibrio cholerae O1 and O139 organisms, or by the recombinant cholera toxin B subunit (CTB). The IgYs were partially purified from egg yolk and orally administered to suckling mice before or after challenge with live O1 or O139 cells. The anti-O1 and O...