Tumor cells, like most other release exosomes called tumor-derived (TEX) and are vital for intercellular communication. TEX membrane-bound extracellular vesicles (EVs), containing unique cargo reminiscent of the parent tumor cells possess immunomodulatory functions. carries factors that directly promote immunosuppression in microenvironment indirectly attract immunosuppressive T-regulatory (Tre...

periodontal disease is a chronic inflammatory disease which represents a primarily anaerobic gram‑negative oral infection that results in gingival inflammation, loss of attachment, bone destruction. bacterial endotoxins in the form of lipopolysaccharides (lps) that are instrumentalin generating a host‑mediated tissue destructive immune response by mobilizing their defensivecells and releasing c...

1 Departamento de Cĺınica Medica, Laboratório de Imunofarmacologia Experimental (LIFE), Instituto de Ciências da Saúde, Universidade Federal do Triângulo Mineiro (UFTM), Rua Vigário Carlos 162, 38025-350 Uberaba, MG, Brazil 2 Instituto de Ciências Biológicas e Naturais, Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, MG, Brazil 3 Universidade Federal de Santa Catarina (UFSC), Florian...