Medullary thyroid cancer accounts for 5-10% of thyroid carcinomas. RET proto-oncogene mutations occur in all of the hereditary MTCs and about 66% of the sporadic MTCs. So, the detection of the RET mutations is necessary for rapid and proper diagnosis and treatment. This systematic review seeks to find a comprehensive list of RET gene mutations in the diagnosis of medullary thyroid cancer. The ...

Despite consensus in focus on form (FOF) instruction over the facilitative role of noticing, controversy has not quelled over ways of directing EFL learners’ attention towards formal features via implicit techniques like input-enhancement or explicit metacognitive feedback and interactive peer-editing on the output they produce. This quasi-experimental study investigated the impact of input enh...

In the background where there are many factors affecting Japanese families such as decrease of children, change family structures, gender concept, etc., "family'' has become a noticeable issue attracting much attention nowadays. The type traditional named "IE'' was officially regulated in law during Meiji period. After war, legal status eliminated; however, reality, still remains popular. fact,...

We evaluated the effect of tamoxifen (TAM) on tumor development in proto-neu transgenic mice that spontaneously develop mammary carcinomas overexpressing the neu protein. These mammary carcinomas are hormone independent because superimposable growth of transplants was observed in females and males. Virgin transgenic mice treated with TAM from 24 weeks of age, ie., when subclinical mammary tumor...

the present article investigates the administrative structure of the pottery mound from an administrative management point of view. data obtained from excavation of the pottery mound has generated an extensive archeological databank relating to the beginning of the historical era with a focus on the emergence of management and administrative systems in the central iranian plateau. in the proto-...

In this paper, we describe our approach taken in the MSM2013 IE Challenge, which was aimed at concept extraction from microposts. The goal of the approach was to combine several existing NER tools which use different classification methods and benefit from their combination. Several NER tools have been chosen and individually evaluated on the challenge training set. We observed that some of the...