Background: Nephrotic Syndrome (NS) is a kidney disorder that causes children body as well adult. Nursing students need to develop their knowledge about caring for with nephrotic through applying the comprehensive nursing syllabus in most schools order promote and skills provide optimum care these children. Aims of study: Assess students’ towards Caring Children Idiopathic find out relationship...

BACKGROUND Nephrotic patients are prone to atherosclerosis in consequence of frequent exposures to hyperlipidemia, hypertension, and immunosuppressive drugs. OBJECTIVES We studied the carotid parameters as early indicators of atherosclerosis in children with nephrotic syndrome. METHODS Between 2008 and 2011, 51 children with history of nephrotic syndrome enrolled in the study. The inclusion...

Nephrotic syndrome, characterized by massive proteinuria, hypoalbuminemia and edema, is one of the most common kidney diseases in children. Although glucocorticoids (GCs), the mainstay of therapy for over 50 years, are effective in most children, more than 20% develop GC resistant nephrotic syndrome (SRNS), among whom focal segmental glomerular sclerosis (FSGS) is a frequent pathological outcom...

ICR-derived strain with glomerulonephritis (ICGN) is a strain of mice with hereditary nephrotic syndrome with an unidentified cause. Based on histopathological and biochemical data, ICGN mice are considered to be a good experimental model for human idiopathic nephrotic syndrome. In the present study, we histochemically investigated the changes in localization of extracellular matrix (ECM) compo...

Idiopathic nephrotic syndrome is the most frequent glomerular disease in children. The mechanisms underlying its pathophysiology have been investigated by genetic, cellular and molecular approaches. While genetic analyses have provided new insights into disease pathogenesis through the discovery of several podocyte genes mutated in distinct forms of inherited nephrotic syndrome, the molecular b...