An ICP-MS validated method for the rapid determination of chromium (Cr), selenium (Se), and molybdenum (Mo) in infant formula and adult nutritional products was successfully transferred from the Agilent 7500cx ICP-MS to the Agilent 7700x ICP-MS, and from lab 1 to lab 2, respectively. The key advantage of the method is that all samples can be analyzed using a single-cell gas mode (helium mode) t...

The complete chemical analysis of natural silicates has previously been accomplished only by combining laser ablation ICP-MS with electron microprobe (EMP) analysis to provide complementary information on major element constituents. Here, we present a method for laser ablation ICP-MS analysis of major elements in silicate glasses and minerals that, when applied using a 193 nm laser system coupl...

Central blood pressure waveforms contain specific features related to cardiac and arterial function. We investigated posture-related changes in ventriculoarterial hemodynamics by means of carotid artery (CA) pulse wave analysis. ECG, brachial cuff pressure, and common CA diameter waveforms (by M-mode ultrasound) were obtained in 21 healthy volunteers (19-30 yr of age, 10 men and 11 women) in su...

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In this study, tablets coming from different police seizures (in Switzerland) were analysed by ICP/MS and ICP/AES. Two methods of preparation were carried out in order to compare the influence of sample preparation. 25 elements were screened by ICP/AES whereas most of the periodic table could be screened by ICP/MS. Approximative detection limits were determined for most of the elements showing,...

LC-MS/MS is widely used in every stage of drug development, from discovery and characterization through manufacturing and quality control of the final pharmaceutical product. Due to its excellent selectivity for complex molecules, LC-MS/MS is an effective tool for both non-target qualitative analysis and quantitative analysis of targeted compounds. However, the sensitivity of LC-MS/MS varies si...

In order to determine low levels of Cd in urine samples, we tried to remove Mo interference using ICP-MS with a dynamic reaction-cell technique, but failed due to the low sensitivity and the variance with the standards. We then performed solid-phase extraction (SPE) before the ICP-MS measurement. A commercially available chelating resin, NOBIAS PA-1, was used for SPE, and could effectively remo...

A new method is described for the analysis of copper (Cu) containing ceruloplasmin (Cp) in human serum. The method uses immunoaffinity plus size-exclusion chromatography (SEC) to separate Cp from other proteins and from inorganic ions, with inductively coupled plasma mass spectrometry (ICP-MS) detection of 63Cu and 65Cu to identify the protein. A reference serum certified for Cp was used to est...

The simultaneous determination of As(III), As(V), and DMA has been performed by ion chromatography (IC) coupled with inductively coupled plasma-mass spectrometry (ICP-MS). The separation of the three arsenic species was achieved by an anionic separator column (AS 7) with an isocratic elution system. The separated species were directly detected by ICP-MS as an element-selective detection method....

The use of analytical techniques is important and critical in all areas related to REE, such as basic fundamental research, exploration, mining, extraction, metallurgical activities at different stages by industries. At every stage these activities, rock, ore, minerals, other materials have be analyzed for their REE contents terms elemental, isotopic, mineralogical concentrations using techniqu...