Osteoporosis is a major healthcare problem that continues growing as the population ages. Sufferers become increasingly susceptible to fractures, which compromise physical and emotional health and increase healthcare costs. Bisphosphonates are the most widely used medicines for the treatment and prevention of postmenopausal osteoporosis. However, therapeutic adherence is suboptimal, meaning tha...

Interest-based negotiation (IBN) is a form of negotiation in which agents exchange information about their underlying goals, with a view to improving the likelihood and quality of a deal. While this intuition has been stated informally in much previous literature, there is no formal analysis of the types of deals that can be reached through IBN and how they differ from those reachable using (cl...

IJKD 2008;2:65-71 www.ijkd.org 1Surgical Kidney Hospital, Ibn Alnafis Medical Complex, Damascus, Syria 2Al-Mouassat Hospital, Damascus University, Damascus, Syria 3Eye Bank, Eye Surgical Hospital, Ibn Alnafis Medical Complex, Damascus, Syria 4Hemodialysis Unit, Damascus Hospital, Damascus, Syria 5Hemodialysis Unit, Douma Hospital, Damascus, Syria 6Gastroenterlogy Department, Ibn Alnafis Hospita...

OBJECTIVE An effective and well tolerated intravenous (IV) bisphosphonate could provide a new treatment method for patients with osteoporosis. The Dosing IntraVenous Administration (DIVA) study was designed to identify the optimal ibandronate IV injection schedule for the treatment of postmenopausal osteoporosis by comparing the efficacy and tolerability of 2- and 3-monthly injections with the ...

Materials with differing surfaces have been developed for clinical implant therapy in dentistry and orthopedics. This study was designed to evaluate bone response to titanium alloy containing Ti-32Nb-5Zr with nanostructure, anodic oxidation, heat treatment, and ibandronate coating. Rats were randomly assigned to two groups for implantation of titanium alloy (untreated) as the control group and ...

Several second-generation bisphosphonates (BPs) are approved in osteoporosis treatment. Efficacy and safety depends on potency of farnesyl pyrophosphate synthase (FPPS) inhibition, hydroxyapatite affinity, compliance and adherence. The latter may be influenced by frequency and route of administration. A literature search using "ibandronate", "postmenopausal osteoporosis", "fracture", and "bone ...

Interest-based negotiation (IBN) is a form of negotiation in which agents exchange information about their underlying goals, with a view to improving the likelihood and quality of a deal. While this intuition has been stated informally in much previous literature, there is no formal analysis of the types of deals that can be reached through IBN and how they differ from those reachable using (cl...

Osteoporosis is a common and debilitating condition associated with significant morbidity and mortality. The efficacy and safety of oral bisphosphonates for the treatment of osteoporosis are well established. However, patient adherence and persistence on treatment are suboptimal. This randomised open-label multi-centre study of 6-months' duration compared persistence on treatment in postmenopau...

Aim: The purpose of the study was to analyze knowledge dentists in Belo Horizonte, Brazil, about bisphosphonates and their clinical implications. Methods: A cross-sectional questionnaire-based conducted with a convenience sample period 8 weeks. questionnaire self-applied structured 10 items dentists’ demographic characteristics, professional profile, bisphosphonates. Associations data were anal...