The loss of numbers and functionality of CD4 T cells is observed in sepsis; however, the mechanism remains elusive. Gene related to anergy in lymphocytes (GRAIL) is critical for the impairment of CD4 T cell proliferation. We therefore sought to examine the role of GRAIL in CD4 T cell proliferation during sepsis. Sepsis was induced in 10-wk-old male C57BL/6 mice by cecal ligation and puncture. S...

BACKGROUND Patient falls and injuries during hospitalization is a good quality indicator of safety of inpatients. Data on inpatients falls are deficient in Egyptian hospitals. Ain Shams university hospitals do not have any recording system for falls. AIM This study aimed at estimating the incidence density of falls and describing pattern and risk factors contributing to falls in Ain shams uni...

In some patients, intracerebral hemorrhage (ICH) causes life-threatening elevations in intracranial pressure (ICP) arising from mass effect of the hematoma and edema. Accordingly, edema is a common endpoint to gauge treatment efficacy in rodent ICH models. Despite widespread reliance on edema, its relationship with ICP and cerebral perfusion pressure (CPP) is unknown. Blood pressure (BP) and IC...

RATIONALE In chronic heart failure, the lung endothelial permeability response to angiotensin II or thapsigargin-induced store depletion is ablated, although the mechanisms are not understood. OBJECTIVES To determine whether the ablated permeability response to store depletion during heart failure was due to impaired expression of store operated Ca2+ channels in lung endothelium. METHODS He...

Three hundred feedlot steers (320 +/- 2 kg) were assigned to freeze brand, hot-iron brand, and sham branding treatments according to a randomized branding arrangement. Behaviors believed to be indicative of pain (i.e., tail-flicking, kicking, falling, and vocalizing) were recorded during branding. Escape behavior, measured as the amount and duration of force exerted on the headgate and squeeze ...

aimed to study the relationship between services provided by university cities and psychological alienation of students residing in it. The research sample consisted (250) male female different social economic levels. is required be from cities, whose stay first year ranges University City, order for realistic them, because with length period, an adaptation process occurs, so student city does ...

http://dx.doi.org/10.1016/j.eswa.2014.01.021 0957-4174/ 2014 Elsevier Ltd. All rights reserved. ⇑ Corresponding author at: Faculty of Science, Ain Shams University, Postal code 11566 Cairo, Egypt. Tel.: +2