Objective: To find out the hypoglycemic activity of Ficus hispida Linn. (bark) in normal and diabetic albino rats and to evaluate its probable mechanism of hypoglycemic activity if any. Material and Methods: Albino rats were divided into groups (n=6) receiving different treatments consisting of vehicle, water-soluble portion of the ethanol extract of Ficus hispida bark (FH) (1.25 g/ kg) and sta...

OBJECTIVE To evaluate the hypoglycemic effect of Brassica juncea (seeds) on streptozotocin induced diabetic male albino rats. METHODS Hypoglycemic activity of Brassica juncea (seeds) aqueous extract at a dose of 250, 350 and 450 mg/kg body weight was evaluated. Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated. RESULTS The serum insulin levels ...

Rao C. A. et al; (2003) evaluated hypoglycemic and antihyperglycemic activity of ethanolic fraction of fruits of Terminalia pallid at different doses in normal and alloxan diabetic rats. The ethanolic extract of fruits of TP at a dose of 0.5 g/kg b.w. could produce a significant fall in blood glucose levels by about 24% in diabetic rats, after 5 h of treatment. But none of these extracts could ...

Mulberry is one of the Chinese traditional medicines. But few studies focused on the hypoglycemic effect of Mulberry seed and the possible mechanisms. We identified that mulberry seed is rich in DNJ, the content of which is 0.6015%. Both mulberry seeds powder and its aqueous extract were used to detect the hypoglycemic effect of mulberry seeds. The results indicated that mulberry seeds powder c...

The effect of several hypoglycemic sulphonylureas upon the oxidative phosphorylation of intact rat liver mitochondria was examined. Following results were obtained and discussed in relation to hypoglycemic action and uncoupling site of these drugs. 1. All hypoglycemic sulphonylurea drugs tested, i.e., tolbutamide, carbutamide, chlorpropamide, acetohexamide, glybenclamide, and glyclopyramide wer...

Aim of the present study was to isolate and characterize the biochemical principle and investigate the hypoglycemic activity of bark of Alangium salviifolium Wang in Alloxan induced hyperglycemic rats. The bark of Alangium salviifolium barks were collected and dried in shade and subjected to extraction with petroleum ether, Chloroform and methanol. Each extracts were subjected to preliminary ph...