BACKGROUND Hyperthyroidism can complicate (mask) the diagnosis of chronic kidney disease (CKD) because it increases glomerular filtration rate and decreases body muscle mass, both of which can lower serum creatinine concentrations. Currently, there is no clinical test that can reliably predict which hyperthyroid cats have concurrent azotemic CKD that will become apparent after treatment of the ...

Free radicals, hydroxyperoxides and H(2)O(2) are all known to damage cell components. This study was designed to compare the concentrations of hydroxyperoxide and free radical scavengers in the cardiac muscles of old rats in the hyper- or hypothyroid condition, to determine whether rates of peroxidation would differ with age, thyroid status, or both. Rats were rendered hyper- or hypothyroid by ...

The osteoporosis associated with human hyperthyroidism has traditionally been attributed to elevated thyroid hormone levels. There is evidence, however, that thyroid-stimulating hormone (TSH), which is low in most hyperthyroid states, directly affects the skeleton. Importantly, Tshr-knockout mice are osteopenic. In order to determine whether low TSH levels contribute to bone loss in hyperthyroi...

Anaerobically periused hearts from rats with experimentally induced hyperthyroidism exhibited accelerated deterioration of pacemaker activity and ventricular performance. The diminished anaerobic performance of hyperthyroid hearts was associated with decreased adenosine triphosphate (ATP) levels and a reduced rate of anaerobic glycolysis as reflected in decreased lactic acid production during 3...

thyroid hoemones effect gastric acid and pepsin secretion.however exact machanism(s) are not clear.this study was performed to compare the effect of vagal stimulation on acid an pepsin secretion in hypothyroid,hyperthyroid and control rars.each group consisted of 8 male and female rats(N-mari) weighing 246+_9 gr.hypo and hyperthyroid states were induced by administretion of methimazol (50mg/l i...

introduction: the aim of this study was to investigate the effect of methimazole on technetium-99m reabsorbing by thyroid gland , it may be possible to perform thyroid scan when the patients are on the methimazole, this can be time saving and decrease the adverse effects of discontinuing methimazole. patients and methods: among all the patients with hyperthyroidism who referred to nuclear medic...

glutamic oxaloacetic transaminase and glutamic pyruvic transaminase activities were measured in experimental thyroid rats. A significant decrease of adrenaline content was found in hyperthyroid group. This finding appears to signify in the explanation of increased responsiveness of the cardiovascular system to adrenaline in hyperthyroidism. Cholinesterase activity was increased in hyperthyroid ...

BACKGROUND Currently, no test can accurately predict the development of azotemia after treatment of hyperthyroidism. Serum cystatin C concentrations (sCysC) might be less influenced by changes in body muscle mass and so better indicate the presence of concurrent chronic kidney disease (CKD) in hyperthyroidism. HYPOTHESES sCysC will be higher in hyperthyroid cats that develop azotemia compared...

The coupling between myocardial beta-adrenergic receptors, adenylate cyclase activity, and the in vivo cardiac response to catecholamines is controversial in hyperthyroidism. The possibility of species differences in beta-adrenoceptor regulation after thyroxine treatment was studied in dogs and in rats. In dogs instrumented with a left ventricular (LV) pressure micromanometer, hyperthyroidism w...