The first in vitro study of seed dormancy breakage Iranian populations St. John’s Wort (Hypericum perforatum) with different geographical origins

Hypericum perforatum is a perennial plant, with worldwide distribution, commonly known as St. John's wort. It has been used for centuries in traditional medicine for the treatment of several disorders, such as minor burns, anxiety, and mild to moderate depression. In the past years, its antidepressant properties have been extensively studied. Despite that, other H. perforatum biological activit...

Plant transformation is an important tool with many applications in modern plant biology. Although this technique is primarily used to produce superior crop varieties, it is also being utilized to answer basic questions concerning gene function and regulation in contemporary functional genomics research. In our laboratory, we have established a transformation system for Hypericum perforatum. Th...

We report a case of liver damage in an elderly patient after the use of herbal products of Hypericum perforatum and copaiba (Copaifera langsdorffii Desf). Hepatotoxicity related to Hypericum perforatum is anecdotally known, but for copaiba, widely used as anti-inflammatory, there is just experimental data in the national literature. This report aimed to draw attention to the possible toxic effe...

Amaç: Bitkilerden elde edilen uçucu yağlar, geleneksel sentetik böcek öldürücülere çevre dostu alternatifler sağlayabilir. Bu çalışmada beş farklı esansiyel yağın (Thymus vulgaris, Piper nigrum, Syzygium aromaticum, Hypericum perforatum, Papaver somniferum) Musca domestica larvalarına karşı etkisinin değerlendirilmesi amaçlanmıştır. Yöntem: Her yağ çeşidinin üç dozu (% 1, % 3 ve 6) tekerrürlü o...

Depression is a common condition in the community with a significant impact on affected individuals, their relatives and society. Many patients with depression do not seek treatment and are often concerned about the possible adverse effects of antidepressant drugs. Extract of Hypericum perforatum (St. John's wort) has long been recognized as a treatment for depression. Several published trials ...

BACKGROUND AND AIMS Hypericum perforatum (St. John's wort) is a widespread Eurasian perennial plant species with remarkable variation in its morphology, ploidy and breeding system, which ranges from sex to apomixis. Here, hypotheses on the evolutionary origin of St. John's wort are tested and contrasted with the subsequent history of interspecific gene flow. METHODS Extensive field collection...

background: dermatophytes are the main cause of human superficial mycosis that is still a public health problem especially in tropical countries such as iran. objective: the aim of this study was determining the antifungal effect of hypercom perforatum essential oil. methods: the minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) for the essential oil of the plant...

In this study, plant oils of Hypericum perforatum, Sesamum indicum, Nigella sative were investigated for their in vitro antibacterial activity against Vibrio anguillarum and Lactococcus garvieae. Antibacterial activity was found to show with oil of Nigella sative. It was determined formed on the diameter of inhibition (inhibition zone: 18 mm) of the oil against Vibrio anguillarum and Lactococcu...

Adhyperforin is a novel constituent of Hypericum perforatum L., but its antidepressant-like activity remains unclear. To explore that, several well-validated animal models of depression as well as neurotransmitter reuptake and transporter binding assays were conducted. The results showed adhyperforin could reduce the immobility time of mice in the forced swimming test and tail suspension assay,...