We studied neurologic morbidity and its evolution during hyperglycemia induced immediately after permanent unilateral common carotid artery ligation in Mongolian gerbils. A total of 60 animals were divided into five groups: one experiencing severe hyperglycemia for 1 hour after the onset of ischemia (brief hyperglycemia group, n = 13), a normoglycemic control group for the brief hyperglycemia g...

BACKGROUND. The appearance of hyperglycemia is due to insulin resistance, functional deficits in the secretion insulin, and a reduction β cell mass. There long-standing debate as relative contribution these factors clinically manifesting dysfunction. aim this study was verify acute effect one factors, mass, on subsequent development hyperglycemia.

BACKGROUND Hyperglycemia in premature infants is associated with increased morbidity and mortality, but data on long-term outcome are limited. We investigated the effects of neonatal hyperglycemia (blood glucose > or = 10 mmol/l, treated with insulin for > or = 12 hours) on growth and neurobehavioral outcome at 2 years of age. METHODS Retrospective follow-up study at 2 years of age among 859 ...

BACKGROUND Blood glucose level continuously fluctuates within a certain range in the human body. In diabetes patients, the extent of such fluctuation is large, despite the strict control of blood glucose. Blood glucose fluctuation has been shown to mediate more adverse effects on vascular endothelial cells and diabetes complications than chronic hyperglycemia, which has been explained as due to...

Although COVID-19 hypothetically, is to cause lethal respiratory disease, yet it led many metabolic co-morbidities including hyperglycemia. New-onset diabetes was observed as one of the more frequent COVID-19. The subjects, who had developed hyperglycemia with raised HbA1c, neither previous nor a family history diabetes, normal levels HbA1c.

BACKGROUND Hyperglycemia associated with critical illness in nondiabetic human patients is a common occurrence in the intensive care unit (ICU), with a reported incidence as high as 71%. HYPOTHESIS Hyperglycemia in critically ill dogs increases the risk of morbidity and mortality. ANIMALS Two hundred forty-five dogs hospitalized in the ICU over a 2-month period were evaluated. METHODS Pro...

Background Hyperglycemia has been considered a predictor of stroke outcomes. In this article we study the correlation between blood glucose levels within the first 24 h after stroke onset and patients' outcomes in mortality and hemorrhagic transformations. Methods Ninety-one non-diabetic patients with acute ischemic stroke admitted to a neurological intensive unit were recruited. Their blood ...

Hyperglycemia during chemotherapy occurs in approximately 10% to 30% of patients. Glucocorticoids and L-asparaginase are well known to cause acute hyperglycemia during chemotherapy. Long-term hyperglycemia is also frequently observed, especially in patients with hematologic malignancies treated with L-asparaginase-based regimens and total body irradiation. Glucocorticoid-induced hyperglycemia o...