ABSTRACT
 In 2020 the number of cases Dengue Hemorrhagic Fever in Indonesia until 49th week reached 95,893 and caused death around 661 people. This study aims to obtain bestformula buccal film by optimizing concentration HPMC K15M Na. CMC evaluation characterization ofpreparations with 3 variations ratios against formulas on Na polymer excipients. include F1 0.67% : 0.33% ; F2 0.65% 0.5% F...

This paper describes the investigation on the effects of separation length and voltage on IEF in a plastic microfluidic device. A LIF, whole-channel imaging detection (WCID) system was developed to monitor proteins while they were moving under an electric field. IEF was carried out in a separation medium consisting of carrier ampholytes and a mixture of linear polymers (hydroxyethylcellulose an...

Hypertension crisis is one of the main health problems and its effective treatment is of high importance. For this purpose, fast-disintegrating and sustained release formulations of captopril, as a drug of choice, were prepared using conventional mucoadhesive polymers hydroxypropyl methylcellulose (HPMC), sodium carboxymethyl cellulose (Na-CMC), hydroxypropyl cellulose (HPC), Carbopol 934 (CP93...

In the present study four minoxidil gels were prepared using carbopol, hydroxypropyl cellulose, hydroxypropyl methylcellulose and combination of hydroxypropyl cellulose, hydroxypropyl methylcellulose for the treatment of alopecia. The gels were evaluated for drug content, viscosity determination, in vitro permeation (across dialysis membrane and mouse skin), skin irritation and stability at 4, ...

Particle and domain sizes strongly influence the properties of materials. Here we present an NMR approach based on paramagnetic relaxation enhancement (PRE) relayed by spin diffusion (SD), which allows us to determine lengths in the nm-μm range. We demonstrate the method on multicomponent organic polymer mixtures by selectively doping one component with a paramagnetic center in order to measure...

This study describes a facile two-step approach to modify the surface of nanoparticles, thereby imparting a core-shell structure to the system. The core consists of magnetic nanoparticles and the shell is composed of thermoresponsive hydroxypropyl cellulose, using a coupling agent to covalently bind the core to the shell. Hydroxypropyl cellulose is known for its biocompatibility and biodegradab...

Phase separated films with controlled porosity were made from ethyl cellulose (EC) and 30% w/w hydroxypropyl cellulose (HPC). The molecular weight of EC can be used to modify the mass transfer rate through coatings by effects on microstructure of the film. Processing conditions are, however, affected by the solution rheology, which could influence the film quality when using different molecular...