background: diabetes mellitus is one of the most important causes of morbidity and mortality all over the world. chronic high blood glucose is the root cause of developing future micro and macro vascular complications. in current study, we analyzed poorly controlled patients’ information by clustering method in order to find more homogenous sub-groups of patients for planning for further interv...

The interaction between two associating hydrophobic particles has traditionally been explained in terms of the release of entropically frustrated hydration shell water molecules. However, this picture cannot account for the kinetics of hydrophobic association and is therefore not capable of providing a microscopic description of the hydrophobic interaction (HI). Here, Monte Carlo simulations of...

The principles obtained from studies on molecular chaperones have provided explanations for the assisted protein folding in vivo. However, the majority of proteins can fold without the assistance of the known molecular chaperones, and little attention has been paid to the potential chaperoning roles of other macromolecules. During protein biogenesis and folding, newly synthesized polypeptide ch...

In the present work, we have explored the use of the triphenylmethyl group, a commonly used protecting group for primary alcohols as a gelling structural component in the design of molecular gelators. We synthesized a small library of triphenylmethyl derivatives of simple primary alcohols and studied their gelation properties in different solvents. Gelation efficiency for some of the derivative...

The trinuclear arene–ruthenium cluster cation [H3Ru3(C6H6)(C6Me6)2(O)] þ, containing a l3-oxo cap and three arene ligand that span a hydrophobic pocket above the metal skeleton, has been crystallised as tetrafluoroborate salt in the presence of variou guest molecules. The host–guest complexes have been characterised by single-crystal X-ray structure analysis. With chloroform a the guest molecul...

anchusa )boraginaceae( includes weedy species in different habitats and cultivations and is composed of four species in iran. species delimitation is mainly based on features as zygomorphic or actinomorphic flowers, straight corolla tube and nutlet shape. in this project, morphological features of different accessions of anchusa species were evaluated. totally, 33 qualitative and quantitative m...

Structure-prediction and hydrophobic-cluster analysis of several starch hydrolases and related enzymes indicated the organization of eleven domain types. Most enzymes possess a catalytic (beta/alpha)8-barrel and a smaller C-terminal domain as seen in crystal structures of alpha-amylase and cyclodextrin glucanotransferase. Some also have a starch-granule-binding domain. Enzymes breaking or formi...