Four human herpesviruses were discovered in a eight-year period between 1986 and 1994. This exciting era of virus discovery was driven in part by the search for HIV and HIV-related diseases coupled with the development of new molecular tools such as PCR, automated Sanger sequencing, and subtractive hybridization. Three of these viruses, human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HH...

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OBJECTIVE We examined the frequency and characteristics of chromosomally integrated human herpesvirus 6 among congenitally infected children. METHODS Infants with and without congenital human herpesvirus 6 infection were prospectively monitored. Cord blood mononuclear cell, peripheral blood mononuclear cell, saliva, urine, and hair follicle samples were examined for human herpesvirus 6 DNA. H...