Background: Cumin (Cuminum cyminum L. [family Apiaceae]) seed essential oil is reported to have antiseptic activity. Until now the antiviral properties of cumin seed extracts on viruses such as herpes simplex virus-1 (HSV-1) have not been studied. The objective of this study was to investigate the in vitro effects of aqueous, methanolic and hydroalcoholic extracts of cumin seed on HSV-1 growth ...

herpes simplex virus type 1 establishes a latent infection in the peripheral nervous system following primary infection. during latent infection, virus genome exhibit limited transcription, with the hsv lats consistently detected in latency infected ganaglia. following ocular infection viral latency develops in the trigeminal ganglia. in this study pcr has been used for detection of hsv-1 nucli...

Avicennia marina (Avicenniaceae) is a species of mangrove tree used for treatment of small pox lesions in Persian folk medicine. The antiviral activity of methanol, ethanol, water, chloroform and n-hexane extracts was evaluated against HIV-1 and HSV. Methanol extract had the highest antiviral activity and the most polar fraction of this extract (fraction D) inhibited HSV with TI and SI values o...

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Herpes Simplex Virus (HSV) is a double-stranded DNA virus in the Herpesviridae family. The most prevalent humans Human Type 1 (HSV-1). It can reach brain without causing symptoms [1]. Currently, antiviral drug used Acyclovir (ACV); nucleotide analogues target polymerase inhibiting viral replication. However, ACV drug-resistant occurs, especially immunocompromised patients [2]. Therefore, altern...

background and aims: sexually transmitted infections (stis) are of major concern to clinicians and researchers in the field of reproductive medicine. many sti pathogens cause incurable and often fatal diseases, and have been transmitted through insemination procedures. the role of herpes simplex virus in male infertility has been investigated using the sensitive methods. the aim of this study w...

Background: Breast cancer develops due to the combination of external and internal risk factors. Also, role viruses is considerable in developing breast cancer. Objectives: This study compared frequency herpes simplex virus types 1 2 (HSV-1 HSV-2) level IgM IgG antibodies against HSV between patients healthy individuals. Methods: Sixty women with 60 (40 fibroadenoma 20 good health) were selecte...

background: it was shown that olive leave extract has antifungal, antibacterial and antiviral activities. the effects of ole on herpes simplex virus-1 (hsv-1) have not been systematically investigated yet. the aim of this study was to examine the in vitro effect of olive leaf hydroalcoholic extract (olhe) on hsv-1.   methods: virucidal effect and viral replication in vero cell line were studied...