Human serum albumin (HSA) is an intrinsic protein and important carrier that transports endogenous as well as exogenous substances across cell membranes. Herein, we have designed and prepared resveratrol (RV)-loaded HSA nanoparticles conjugating RGD (arginine-glycine-aspartate) via a polyethylene glycol (PEG) "bridge" (HRP-RGD NPs) for highly effective targeted pancreatic tumor therapy. HRP-RGD...

We show that 4-dimensional conjugation manifolds are all obtained from branched 2-fold coverings of knotted surfaces in Z2-homology 4-spheres.

We discuss the possibility of observing atomic phase conjugation from Bose condensates, and using it as a diagnostic tool to access the spatial coherence properties and to measure the lifetime of the condensate. We argue that since phase conjugation results from the scattering of a partial matter wave off the spatial grating produced by two other waves, it offers a natural way to directly measu...

She notices the formal similarity between the stem tuk‘attachINTRANS’ in (1a) and tuke‘attachTRANS’ in (1b). These two represent the two main verb conjugations in Japanese: tukrepresents the consonant stem or godan conjugation, while tukerepresents the vowel stem or ichidan conjugation. The learner also notices the grammatical relationship between the two stems: tukis the intransitive and tuket...

Immobilization of single antioxidant enzyme systems was frequently studied in the past, however, there is a lack reliable reports on co-immobilization such enzymes. Here, an cascade involving superoxide dismutase (SOD) and horseradish peroxidase (HRP) successfully immobilized titania nanosheets (TNS) by sequential adsorption method using poly(diallyldimethylammonium chloride) (PDADMAC) poly(sty...

Hepatoma-derived growth factor-related proteins (HRP) comprise a family of 6 members, which the biological functions are still largely unclear. Here we show that during embryogenesis HRP-3 is strongly expressed in the developing nervous system. At early stages of development HRP-3 is located in the cytoplasm and neurites of cortical neurons. Upon maturation HRP-3 relocalizes continuously to the...

The (pro)renin receptor [(P)RR] is implicated in organ pathology. We examined the cellular location of the (P)RR and whether a putative (P)RR antagonist, RILLKKMPSV, corresponding to the handle region of the prorenin prosegment (handle region peptide [HRP]) influences angiogenesis, inflammation, and neuronal and glial function in rat retina. The (P)RR was localized to retinal vessels, endotheli...

The main objective of this study was to determine the pathways by which horseradish peroxidase (HRP) can cross the endothelium of muscle capillaries. Specimens of mouse diaphragm were fixed for cytochemical analysis at various intervals after intervenous injection of 0.5 mg HRP, at 4 min after intervenous injection of varied amounts of HRP, and at 4 min after intervenous injections in various ...